DOK1 and MAP4K4

  • Number of citations of the paper that reports this interaction (PubMedID 10669731)
  • 45
  • Data Source:
  • HPRD (in vivo)

DOK1

MAP4K4

Description docking protein 1 mitogen-activated protein kinase kinase kinase kinase 4
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease ( 30636644)
  • Asthma ( 31619474)
  • Asthma (time to onset) ( 27130862)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
  • White blood cell count ( 32888494)
Interacting Genes 42 interacting genes: ABL1 ABL2 BCR CRK CRKL CSDE1 CSK DOK3 ERBB2 FES FGR FYN GRB10 HCK INPP5D INSR ITGB1 ITGB2 ITGB3 ITGB5 ITGB7 ITK KIT LCK LYN MAP4K4 NCK1 NCK2 PIK3R1 PLCG1 PTK6 PTPN6 PTPRH RASA1 RET SH2D1A SHC1 SRC TEC TLN1 VAV1 YES1 18 interacting genes: BRCA1 CASP8 DOK1 GBP3 H2BC21 ITGB1 KIF26B KIF5A MAP3K7 NCK1 NME7 PPP1CA PPP1CC PRKCE RAP2A RASA1 SLC9A1 TBPL2
Entrez ID 1796 9448
HPRD ID 04228 05235
Ensembl ID ENSG00000115325 ENSG00000071054
Uniprot IDs B3KP83 B4DJN1 Q14CB2 Q2TA81 Q99704 B7Z3V5 O95819 V9HWH3
PDB IDs 2V76 4OBO 4OBP 4OBQ 4RVT 4U3Y 4U3Z 4U40 4U41 4U42 4U43 4U44 4U45 4ZK5 4ZP5 5DI1 5J95 5W5Q
Enriched GO Terms of Interacting Partners?
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