DOCK3 and RAC1

  • Number of citations of the paper that reports this interaction (PubMedID 32203420)
  • 21
  • Data Source:
  • BioGRID (fluorescent resonance energy transfer)

DOCK3

RAC1

Description dedicator of cytokinesis 3 Rac family small GTPase 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age at first birth ( 34211149)
  • Asthma ( 32296059)
  • Bacteremia ( 27236921)
  • Blood protein levels ( 28240269)
  • Body fat distribution (arm fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • Body fat mass ( 28552196)
  • Brain morphology (min-P) ( 32665545)
  • Brain morphology (MOSTest) ( 32665545)
  • Caffeine consumption from coffee or tea ( 33287642)
  • Cholangiocarcinoma in primary sclerosing cholangitis (time to event) ( 28779025)
  • Cocaine dependence ( 31212010)
  • Colorectal cancer ( 29228715)
  • Cortical surface area (MOSTest) ( 32665545)
  • Depressive symptom (appetite changes) (binary trait) ( 31530331)
  • Depressive symptoms (binary sum-score) ( 31530331)
  • Depressive symptoms (sum-score) ( 31530331)
  • Eosinophil counts ( 32888494 27863252)
  • Eosinophil percentage of granulocytes ( 27863252)
  • Eosinophil percentage of white cells ( 32888494 27863252)
  • Estimated glomerular filtration rate ( 31152163)
  • Height ( 20881960 25282103)
  • Hip circumference adjusted for BMI ( 34021172)
  • Melanoma ( 24980573)
  • Morning person ( 30696823)
  • Refractive error ( 32231278)
  • Subcortical volume (min-P) ( 32665545)
  • Subcortical volume (MOSTest) ( 32665545)
  • Sum eosinophil basophil counts ( 27863252)
  • Trunk fat mass ( 28552196)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI in non-smokers ( 28443625)
  • Waist circumference adjusted for body mass index ( 34021172)
  • Apolipoprotein A1 levels ( 32203549)
  • Basal cell carcinoma ( 31174203)
  • Body mass index ( 26426971)
  • Coronary artery disease ( 29212778)
  • Keratinocyte cancer (MTAG) ( 31174203)
  • LDL cholesterol levels ( 32203549)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Red cell distribution width ( 27863252)
Interacting Genes 10 interacting genes: CALM1 CRK HOXA1 KHDRBS1 NR3C1 PLEKHF2 PSEN1 PSEN2 RAC1 SRPK2 182 interacting genes: ACTA1 ACTB AGAP1 AGAP2 AKT1 ARAP1 ARAP2 ARFIP2 ARHGAP1 ARHGAP12 ARHGAP15 ARHGAP17 ARHGAP20 ARHGAP22 ARHGAP23 ARHGAP27 ARHGAP31 ARHGAP32 ARHGAP33 ARHGAP35 ARHGAP39 ARHGAP4 ARHGAP44 ARHGAP9 ARHGDIA ARHGDIB ARHGDIG ARHGEF10 ARHGEF2 ARHGEF25 ARHGEF26 ARHGEF4 ARHGEF7 ARL2BP BAG6 BAIAP2 BCR BIRC2 BRINP1 CASP3 CASP7 CAV1 CDC23 CDC42BPG CDC42SE1 CDC42SE2 CFAP36 CHN1 CHN2 CIT COG5 CORO1C CSN2 CYBA CYBB CYFIP1 DEF6 DIAPH1 DIAPH3 DMPK DNMBP DOCK1 DOCK2 DOCK3 DOCK7 DOCK8 DVL1 DVL2 EIF2AK2 ENAH FAM13A FAM13B FGD5 FHOD1 FLNA FMN2 FMNL1 GMIP GRN HACD3 HACE1 HDAC7 HPS4 ICMT IFNGR1 IL1RAP IQGAP1 IQGAP2 KPNA4 KPNA6 KRT40 KTN1 LATS1 LRP2 LTBP3 LTBP4 LZTS2 MAGI1 MAP3K10 MAP3K11 MAP3K4 MCF2 MCF2L MCM3AP MDFI METAP2 MT-CO3 MTNR1A MYD88 MYH9 NCF2 NCK1 NCKAP1 NEDD4 NME1 NOS2 NOXA1 NR2C2 OCRL OPHN1 PAK1 PAK2 PAK3 PAK5 PAK6 PARD6A PARD6B PARD6G PIAS3 PIK3R1 PIP4K2A PLD1 PLEKHG1 PLEKHG2 PLEKHG6 PLXNB1 PPP2R2B PREX1 PREX2 PRKCA PRKCD PRKCI PRKN PRMT6 PTK2 RACGAP1 RALBP1 RAP1GDS1 RASGRF1 RASGRF2 RCC2 RGL2 RPS6KB1 SET SFPQ SH3BP1 SH3RF1 SH3RF3 SNX31 SRGAP1 SRGAP3 STAT1 STAT3 STAU1 SYDE2 SYNJ2 TBC1D3F TIAM1 TLR2 TNFRSF12A TRIO TUBA4A UBC UNKL USH1C USP6 VAV1 VAV2 VAV3 VWF WAS WASF1
Entrez ID 1795 5879
HPRD ID 10341 03627
Ensembl ID ENSG00000088538 ENSG00000136238
Uniprot IDs Q8IZD9 A4D2P0 A4D2P1 P63000
PDB IDs 1E96 1FOE 1G4U 1HE1 1HH4 1I4D 1I4L 1I4T 1MH1 1RYF 1RYH 2FJU 2H7V 2NZ8 2P2L 2RMK 2VRW 2WKP 2WKQ 2WKR 2YIN 3B13 3BJI 3RYT 3SBD 3SBE 3SU8 3SUA 3TH5 4GZL 4GZM 4YON 5FI0 5HZH 5N6O 5O33 5QQD 5QQE 5QQF 5QQG 5QQH 5QQI 5QQJ 5QQK 5QQL 5QQM 5QQN 5QU9 6AGP 6BC1 6TGC 6X1G 7AJK
Enriched GO Terms of Interacting Partners?
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