DOCK3 and PSEN2

  • Number of citations of the paper that reports this interaction (PubMedID 10854253)
  • 26
  • Data Source:
  • HPRD (in vitro, two hybrid)

DOCK3

PSEN2

Description dedicator of cytokinesis 3 presenilin 2
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age at first birth ( 34211149)
  • Asthma ( 32296059)
  • Bacteremia ( 27236921)
  • Blood protein levels ( 28240269)
  • Body fat distribution (arm fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • Body fat mass ( 28552196)
  • Brain morphology (min-P) ( 32665545)
  • Brain morphology (MOSTest) ( 32665545)
  • Caffeine consumption from coffee or tea ( 33287642)
  • Cholangiocarcinoma in primary sclerosing cholangitis (time to event) ( 28779025)
  • Cocaine dependence ( 31212010)
  • Colorectal cancer ( 29228715)
  • Cortical surface area (MOSTest) ( 32665545)
  • Depressive symptom (appetite changes) (binary trait) ( 31530331)
  • Depressive symptoms (binary sum-score) ( 31530331)
  • Depressive symptoms (sum-score) ( 31530331)
  • Eosinophil counts ( 32888494 27863252)
  • Eosinophil percentage of granulocytes ( 27863252)
  • Eosinophil percentage of white cells ( 32888494 27863252)
  • Estimated glomerular filtration rate ( 31152163)
  • Height ( 20881960 25282103)
  • Hip circumference adjusted for BMI ( 34021172)
  • Melanoma ( 24980573)
  • Morning person ( 30696823)
  • Refractive error ( 32231278)
  • Subcortical volume (min-P) ( 32665545)
  • Subcortical volume (MOSTest) ( 32665545)
  • Sum eosinophil basophil counts ( 27863252)
  • Trunk fat mass ( 28552196)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI in non-smokers ( 28443625)
  • Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes 10 interacting genes: CALM1 CRK HOXA1 KHDRBS1 NR3C1 PLEKHF2 PSEN1 PSEN2 RAC1 SRPK2 61 interacting genes: AAMP ACTG1 AP1G1 APH1A APH1B APP AURKA BCL2L1 CAPN1 CASP1 CASP3 CASP6 CASP7 CASP8 CEP55 CFLAR CHKA CIB1 CSNK1A1 CSNK1D CSNK2A1 CTNNB1 CTNND2 DNAJB1 DOCK3 ECD EID1 ELAVL1 EVI5L EXOC6 FBXL12 FHL2 FLNA FLNB GCDH GFAP HLA-DMB HPS1 ICAM5 IFIT3 IFIT5 KCNIP3 KCNIP4 LIPF MAST1 METTL2B NCSTN NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 OGA PDCD4 PSENEN RAB11A RHEB RNF32 SPC24 SRI UBQLN1
Entrez ID 1795 5664
HPRD ID 10341 02860
Ensembl ID ENSG00000088538 ENSG00000143801
Uniprot IDs Q8IZD9 P49810
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?