DOCK2 and VAV1

  • Number of citations of the paper that reports this interaction (PubMedID 12393632)
  • 25
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vitro)

DOCK2

VAV1

Description dedicator of cytokinesis 2 vav guanine nucleotide exchange factor 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acne (severe) ( 24927181)
  • Body mass index and waist-hip ratio (pleiotropy) ( 29868124)
  • Coronary artery aneurysm in Kawasaki disease ( 33772158)
  • Placental abruption ( 29884306)
  • Pneumococcal bacteremia ( 27236921)
  • Prostate cancer ( 29892016)
  • Protein quantitative trait loci ( 18464913)
Interacting Genes 49 interacting genes: CALCOCO2 CARD10 CCNDBP1 CD247 CRKL CYSRT1 ELMO1 GNAL GOLGA6L9 HNRNPK HOXA1 KHDRBS1 KHDRBS2 KHDRBS3 KRT31 KRT34 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP17-1 KRTAP3-1 KRTAP3-3 KRTAP4-2 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-4 MDFI MTDH MTUS2 NBPF19 NOTCH2NLA PAK2 PCSK5 PLEKHF2 PLSCR1 RAC1 RAC2 TENM4 TGM1 TRIM23 VAV1 82 interacting genes: ABL1 ACTA1 AOC3 AR ARHGDIA ARHGDIB BCR BLNK BTK CASP3 CBL CBLB CD19 CDC42 CRK CXCR4 DNM2 DOCK2 DOK1 EGFR EMD EPOR ERBB2 ERBB3 ERBB4 EZH2 FGFR1 FYN GAB1 GRB2 HCK HNRNPK HRAS IL6ST INSR JAK2 JUN KHDRBS1 LAT LCK LCP2 MAPK1 MERTK MET NEK3 PAG1 PDGFRB PHAX PIK3R1 PLCG1 PRKCQ PRLR PTK2B PTPN22 PTPN6 PTPRC RAC1 RACGAP1 RAF1 RHOA RHOG RIMS1 S100B SH3BP2 SHB SHC1 SIAH1 SIAH2 SLA SMARCA4 SOCS1 SYK TEC TUBA1A TUBA4A TUBB TYK2 XRCC5 XRCC6 ZAP70 ZNF655 ZYX
Entrez ID 1794 7409
HPRD ID 09121 01284
Ensembl ID ENSG00000134516 ENSG00000141968
Uniprot IDs Q5XG91 Q92608 A0A0A0MR07 B2R8B5 P15498 Q96D37
PDB IDs 2RQR 2YIN 3A98 3B13 6TGB 6TGC 2CRH 2LCT 2MC1 2ROR 3BJI 3KY9 6NEW 6NF1 6NFA
Enriched GO Terms of Interacting Partners?
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