DMD and KRT19

Number of citations of the paper that reports this interaction (PubMedID 16000376)
33

Data Source:
HPRD (in vivo, in vitro)

		DMD	KRT19
Description		dystrophin	keratin 19
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Cell Surface Dystrophin-associated Glycoprotein Complex Syntrophin Complex Lateral Plasma Membrane Z Disc Cell Junction Cell-substrate Junction Filopodium Cortical Actin Cytoskeleton Filopodium Membrane Protein-containing Complex Sarcolemma Cell Projection Costamere Neuron Projection Terminus Membrane Raft Synapse Postsynaptic Membrane	Cytosol Intermediate Filament Plasma Membrane Dystrophin-associated Glycoprotein Complex Apicolateral Plasma Membrane Z Disc Sarcolemma Costamere Extracellular Exosome Cell Periphery Terminal Web
	Molecular Function	Dystroglycan Binding Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Zinc Ion Binding Structural Constituent Of Muscle Myosin Binding Vinculin Binding Nitric-oxide Synthase Binding Actin Filament Binding	Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Muscle Protein-containing Complex Binding
	Biological Process	Regulation Of Heart Rate Cytoskeleton Organization Muscle Organ Development Skeletal Muscle Tissue Development Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Regulation Of Skeletal Muscle Contraction Actin Cytoskeleton Organization Negative Regulation Of Peptidyl-serine Phosphorylation Cellular Protein Localization Cellular Protein-containing Complex Assembly Maintenance Of Blood-brain Barrier Response To Muscle Stretch Peptide Biosynthetic Process Muscle Cell Cellular Homeostasis Neuron Development Muscle Cell Development Cardiac Muscle Contraction Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cardiac Muscle Cell Action Potential Regulation Of Muscle System Process Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Peptidyl-cysteine S-nitrosylation Positive Regulation Of Sodium Ion Transmembrane Transporter Activity	Notch Signaling Pathway Response To Estrogen Sarcomere Organization Cell Differentiation Involved In Embryonic Placenta Development
Pathways		Non-integrin membrane-ECM interactions Striated Muscle Contraction	Keratinization Formation of the cornified envelope
Drugs		Golodirsen
Diseases
GWAS		Ankle-brachial index ( 31388106) Anxiety in major depressive disorder ( 24047446) Body mass index ( 28892062) Influenza A (H1N1) infection ( 26379185) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Major depressive disorder ( 34099189) Mild influenza (H1N1) infection ( 26379185) Response to anti-depressant treatment in major depressive disorder ( 22041458) Temporomandibular joint disorder ( 28081371) Waist circumference ( 28552196)
Interacting Genes		30 interacting genes: ACTA1 ACTC1 APP CADPS CADPS2 CDC25A CTNNAL1 DAG1 DGKZ DISC1 DTNA DTNB FASLG HAUS1 HNF4A KCNJ12 KRT19 KRT8 MAP3K5 PGM5 PICK1 SGCZ SNTA1 SNTB1 SNTB2 SNTG1 SNTG2 TRAF3IP1 TRIM63 UTRN	76 interacting genes: ABI2 AMOT AMOTL2 ARL4A BEX2 C1orf109 CARD9 CCDC146 CCHCR1 CEP57L1 COPS4 DEPP1 DGCR6L DMD EIF4E2 EIF4ENIF1 ESR1 EXOC8 FAM107A FAM124B FANCG GFAP GLYCTK HAUS1 HGS IKZF3 KDM1A KIFC3 KRT1 KRT15 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT77 KRT78 KRT79 KRT80 KRT81 KRT83 KRT85 KRT86 LENG1 LGALS14 NFKBID PCDHB12 PCM1 PKN1 PLEKHA5 PNN POLL POLR1C PPP1R18 PSMA1 RCOR3 SFI1 SGF29 SMARCB1 SMARCE1 SNAPIN SPG21 TBC1D7 TCHP TFPT TUBG1 UBE2I UCHL5 USHBP1 ZNF638
Entrez ID		1756	3880
HPRD ID		02303	01007
Ensembl ID		ENSG00000198947	ENSG00000171345
Uniprot IDs		A0A0S2Z3B5 A0A0S2Z3J7 A7E212 P11532 Q16484 Q4G0X0	P08727
PDB IDs		1DXX 1EG3 1EG4 3UUN
Enriched GO Terms of Interacting Partners?
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