CCDC116 and MEIS3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CCDC116	MEIS3
Description		coiled-coil domain containing 116	Meis homeobox 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome	Chromatin Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process		Eye Development Regulation Of Transcription By RNA Polymerase II Brain Development Positive Regulation Of Cell Population Proliferation Embryonic Pattern Specification Animal Organ Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Kinase B Signaling Negative Regulation Of Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Ulcerative colitis ( 28067908) White blood cell count ( 32888494)
Interacting Genes		32 interacting genes: AKAP9 BEX3 CARD10 CCDC85B CDCA7L CEP20 CEP44 COG6 CSNK2A1 CTAG1A CTAG1B FAM9B GOLGA6L9 HSF2BP IGFBP6 KRT31 KRT40 KRTAP4-12 MDFI MEIS3 MTUS2 NUTM1 PKNOX2 PPP1R16A RASSF10 SLC2A4 TADA2A TFIP11 TRAF1 USHBP1 ZMYND12 ZNF655	22 interacting genes: ATXN1L CCDC116 ENKD1 FAM110A FAM110B FAM161B FAM90A1 HGS HOXA13 INTS4 LENG1 LMO3 MBD3 PIP4K2A PRPF31 PSORS1C2 SUOX TCL1B TLE5 TSGA10IP VEZF1 ZNF417
Entrez ID		164592	56917
HPRD ID		08203	14386
Ensembl ID		ENSG00000161180	ENSG00000105419
Uniprot IDs		Q8IYX3	A0A024R0S2 A0A024R0W2 H0YNA8 Q49A38 Q99687
PDB IDs
Enriched GO Terms of Interacting Partners?
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