MEIS3 and SUOX

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MEIS3	SUOX
Description		Meis homeobox 3	sulfite oxidase
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Mitochondrion Mitochondrial Intermembrane Space Mitochondrial Matrix
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Sulfite Oxidase Activity Heme Binding Molybdenum Ion Binding Molybdopterin Cofactor Binding
	Biological Process	Eye Development Regulation Of Transcription By RNA Polymerase II Brain Development Positive Regulation Of Cell Population Proliferation Embryonic Pattern Specification Animal Organ Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Kinase B Signaling Negative Regulation Of Apoptotic Signaling Pathway	Sulfur Compound Metabolic Process
Pathways			Sulfide oxidation to sulfate
Drugs			{[2-Amino-4-oxo-6,7-di(sulfanyl-ÎºS)-3,5,5a,8,9a,10-hexahydro-4H-pyrano[3,2-g]pteridin-8-yl]methyl dihydrogenato(2-) phosphate}(dioxo)sulfanylmolybdenum
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Anorexia nervosa ( 28494655) Asthma ( 31959851 32296059 31619474) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Asthma or allergic disease (pleiotropy) ( 29785011) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Gastroesophageal reflux disease ( 31527586) Intelligence (MTAG) ( 29326435) Medication use (glucocorticoids) ( 31015401) Pediatric autoimmune diseases ( 26301688) Polycystic ovary syndrome ( 22885925) Refractive error ( 32231278) Type 1 diabetes ( 18198356 31152121) Vitiligo ( 22951725)
Interacting Genes		22 interacting genes: ATXN1L CCDC116 ENKD1 FAM110A FAM110B FAM161B FAM90A1 HGS HOXA13 INTS4 LENG1 LMO3 MBD3 PIP4K2A PRPF31 PSORS1C2 SUOX TCL1B TLE5 TSGA10IP VEZF1 ZNF417	82 interacting genes: ACOT11 BAG4 C1D C5orf51 CAMK2A CAP1 CCDC103 CDCA4 CEP76 COA7 COPS8 CRX CTAG1A CTAG1B CYB5R2 DMAP1 DUSP21 EIF3F ERICH4 EYA2 FAM217B FMNL2 FMR1 FNDC3B GOLGA6L9 HADHB HMG20A INCA1 ING5 ISCA2 ITGB3BP KIAA0753 KRT26 KRT27 KRT34 KRT4 KRT40 LMO4 MAGEA11 MAGEB10 MBD3L1 MDFI MED28 MEIS3 MORN3 MRPS35 MYL7 MYO1B NUP62 PEX19 PIH1D2 POMC PRRX1 PTTG2 REL RELA RHOH RINT1 RNF41 RPLP1 RSKR RUSC1 SERTAD3 SGTA SH3BP5L SNF8 SOHLH1 SPC24 STAT5B STH SYNGAP1 TAS2R7 TEX12 TRIB3 TSC1 UBQLN2 UBR2 VBP1 VPS28 ZNF143 ZNF576 ZXDC
Entrez ID		56917	6821
HPRD ID		14386	06055
Ensembl ID		ENSG00000105419	ENSG00000139531
Uniprot IDs		A0A024R0S2 A0A024R0W2 H0YNA8 Q49A38 Q99687	A0A024RB79 P51687
PDB IDs			1MJ4
Enriched GO Terms of Interacting Partners?
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