ACE and DCAF7

ACE

DCAF7

Description angiotensin I converting enzyme DDB1 and CUL4 associated factor 7
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adventurousness ( 30643258)
  • Alzheimer's disease (late onset) ( 24162737 30820047)
  • Alzheimer's disease or family history of Alzheimer's disease ( 33589840)
  • Angiotensin-converting enzyme activity ( 20066004)
  • Blood metabolite levels ( 24816252)
  • Blood metabolite ratios ( 24816252)
  • Blood protein levels ( 30072576)
  • Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798)
  • Diastolic blood pressure ( 28135244 27841878 28739976)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Hodgkin's lymphoma ( 34216518)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Medication use (calcium channel blockers) ( 31015401)
  • Metabolic traits ( 21886157)
  • Metabolite levels ( 23281178)
  • Serum metabolite levels ( 33031748 24625756 23093944)
  • Systolic blood pressure ( 27841878 30578418)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Type 2 diabetes ( 30297969)
  • Hip circumference adjusted for BMI ( 34021172)
Interacting Genes 5 interacting genes: AGTR2 BDKRB2 COMT CSNK2A1 DCAF7 17 interacting genes: ACE AIFM1 APP ATP13A2 ATP5PD BMPR1B CBX1 DYRK1B LIG1 PCTP PWP2 SPDYA TANC2 TK1 TLK2 YWHAB YWHAG
Entrez ID 1636 10238
HPRD ID 00108 09340
Ensembl ID ENSG00000159640 ENSG00000136485
Uniprot IDs B4DKH4 P12821 P61962
PDB IDs 1O86 1O8A 1UZE 1UZF 2C6F 2C6N 2IUL 2IUX 2OC2 2XY9 2XYD 2YDM 3BKK 3BKL 3L3N 3NXQ 4APH 4APJ 4BXK 4BZR 4BZS 4C2N 4C2O 4C2P 4C2Q 4C2R 4CA5 4CA6 4UFA 4UFB 5AM8 5AM9 5AMA 5AMB 5AMC 6EN5 6EN6 6F9R 6F9T 6F9U 6F9V 6H5W 6H5X 6QS1 6TT1 6TT3 6TT4 6ZPQ 6ZPT 6ZPU
Enriched GO Terms of Interacting Partners?
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