CYP11A1 and ETFA

		CYP11A1	ETFA
Description		cytochrome P450 family 11 subfamily A member 1	electron transfer flavoprotein subunit alpha
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix	Mitochondrion Mitochondrial Matrix
	Molecular Function	Iron Ion Binding Protein Binding Cholesterol Monooxygenase (side-chain-cleaving) Activity Heme Binding	Protein Binding Electron Transfer Activity Oxidoreductase Activity Flavin Adenine Dinucleotide Binding
	Biological Process	C21-steroid Hormone Biosynthetic Process Glucocorticoid Biosynthetic Process Cholesterol Metabolic Process Sterol Metabolic Process Cortisol Metabolic Process Vitamin D Metabolic Process Cellular Response To Peptide Hormone Stimulus	Electron Transport Chain Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase
Pathways		Pregnenolone biosynthesis Endogenous sterols Defective CYP11A1 causes AICSR	Respiratory electron transport
Drugs		Aminoglutethimide
Diseases
GWAS		Coffee consumption (cups per day) ( 31837886) Craniofacial microsomia ( 26853712) Diisocyanate-induced asthma ( 25918132)	Diverticular disease ( 30177863) Glioma ( 28346443) Heel bone mineral density ( 30598549) Non-glioblastoma glioma ( 28346443 26424050) Response to tocilizumab in rheumatoid arthritis ( 22491018)
Interacting Genes		6 interacting genes: CYP11B2 ETFA FDX1 SMAD2 SMAD3 SMAD9	15 interacting genes: BNC1 CDC42 CHRNA3 COX7C CSK CYP11A1 ETFB FAH FBXL17 HSPB2 LINC00597 MOV10L1 PSEN1 TNFRSF11A VCAM1
Entrez ID		1583	2108
HPRD ID		00326	01979
Ensembl ID		ENSG00000140459	ENSG00000140374
Uniprot IDs		A0A0S2Z3R3 P05108	A0A0S2Z3L0 P13804
PDB IDs		3N9Y 3N9Z 3NA0 3NA1	1EFV 1T9G 2A1T 2A1U
Enriched GO Terms of Interacting Partners?
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