AK8 and CNTF

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		AK8	CNTF
Description		adenylate kinase 8	ciliary neurotrophic factor
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Axoneme Sperm Flagellum 9+2 Motile Cilium	Extracellular Region Extracellular Space Cytoplasm Axon
	Molecular Function	Adenylate Kinase Activity Cytidylate Kinase Activity Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding AMP Binding	Cytokine Activity Ciliary Neurotrophic Factor Receptor Binding Interleukin-6 Receptor Binding Protein Binding Growth Factor Activity Protein-containing Complex Binding
	Biological Process	Nucleoside Diphosphate Phosphorylation Nucleoside Triphosphate Biosynthetic Process Ventricular System Development Nucleoside Monophosphate Phosphorylation	Signal Transduction Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Photoreceptor Cell Differentiation Regulation Of Retinal Cell Programmed Cell Death Astrocyte Activation Muscle Organ Morphogenesis Neuron Development Positive Regulation Of Axon Regeneration Ciliary Neurotrophic Factor-mediated Signaling Pathway
Pathways		Interconversion of nucleotide di- and triphosphates	IL-6-type cytokine receptor ligand interactions
Drugs		Bis(Adenosine)-5'-Pentaphosphate
Diseases
GWAS		Obesity-related traits ( 23251661)	Diastolic blood pressure ( 27841878) Inflammatory bowel disease ( 23128233) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878) Ulcerative colitis ( 28067908)
Interacting Genes		17 interacting genes: ALKBH3 CCDC102B CDK18 CNTF DPY30 FBXO7 HAUS1 MAP3K7CL MCM7 MID1IP1 PRMT6 PRRC2B RBM39 SMG9 SYT17 UBE2Z ZMAT2	14 interacting genes: AK8 APOE CNTFR CYSRT1 IL6R IL6ST KRT31 KRT40 LIFR NDUFAB1 RDM1 TEPSIN TIMM10 TRIP6
Entrez ID		158067	1270
HPRD ID		12991	00347
Ensembl ID		ENSG00000165695	ENSG00000242689
Uniprot IDs		Q96MA6	P26441
PDB IDs			1CNT
Enriched GO Terms of Interacting Partners?
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