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CNTF

Description ciliary neurotrophic factor
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Extracellular Space
  • Cytoplasm
  • Axon
Molecular Function
  • Cytokine Activity
  • Ciliary Neurotrophic Factor Receptor Binding
  • Interleukin-6 Receptor Binding
  • Protein Binding
  • Growth Factor Activity
  • Protein-containing Complex Binding
Biological Process
  • Signal Transduction
  • Positive Regulation Of Cell Population Proliferation
  • Positive Regulation Of Gene Expression
  • Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein
  • Negative Regulation Of Neuron Apoptotic Process
  • Negative Regulation Of Photoreceptor Cell Differentiation
  • Regulation Of Retinal Cell Programmed Cell Death
  • Astrocyte Activation
  • Muscle Organ Morphogenesis
  • Neuron Development
  • Positive Regulation Of Axon Regeneration
  • Ciliary Neurotrophic Factor-mediated Signaling Pathway
Pathways
  • IL-6-type cytokine receptor ligand interactions
Drugs
Diseases
GWAS
  • Diastolic blood pressure ( 27841878)
  • Inflammatory bowel disease ( 23128233)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Pulse pressure ( 27841878)
  • Systolic blood pressure ( 27841878)
  • Ulcerative colitis ( 28067908)
Interacting Genes 14 interacting genes: AK8 APOE CNTFR CYSRT1 IL6R IL6ST KRT31 KRT40 LIFR NDUFAB1 RDM1 TEPSIN TIMM10 TRIP6
Entrez ID 1270
HPRD ID 00347
Ensembl ID ENSG00000242689
Uniprot IDs P26441
PDB IDs 1CNT
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025