CYP3A5 and ATOH8

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		CYP3A5	ATOH8
Description		cytochrome P450 family 3 subfamily A member 5	atonal bHLH transcription factor 8
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Intracellular Membrane-bounded Organelle	Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Speck
	Molecular Function	Monooxygenase Activity Iron Ion Binding Protein Binding Steroid Hydroxylase Activity Retinoic Acid 4-hydroxylase Activity Oxidoreductase Activity Oxygen Binding Heme Binding Testosterone 6-beta-hydroxylase Activity Aromatase Activity Estrogen 16-alpha-hydroxylase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Dimerization Activity E-box Binding DNA-binding Transcription Factor Binding
	Biological Process	Lipid Hydroxylation Xenobiotic Metabolic Process Steroid Metabolic Process Estrogen Metabolic Process Alkaloid Catabolic Process Xenobiotic Catabolic Process Retinol Metabolic Process Retinoic Acid Metabolic Process Aflatoxin Metabolic Process Oxidative Demethylation	Formation Of Primary Germ Layer Negative Regulation Of Endothelial Cell Proliferation Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Endothelial Cell Migration Negative Regulation Of Gene Expression Neuron Differentiation Tube Formation Positive Regulation Of Endothelial Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Myoblast Proliferation SMAD Protein Signal Transduction Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Pathways		Xenobiotics Aflatoxin activation and detoxification
Drugs		Cannabidiol Diacerein Nabiximols
Diseases
GWAS		Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Platelet count ( 29403010) Serum metabolite levels ( 33031748 23093944) Ticagrelor levels in individuals with acute coronary syndromes treated with ticagrelor ( 25935875) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)	Blood metabolite levels ( 31502714) Optic disc size ( 31809533)
Interacting Genes		3 interacting genes: ATOH8 ETV5 RDH13	1 interacting genes: CYP3A5
Entrez ID		1577	84913
HPRD ID		05617	09813
Ensembl ID		ENSG00000106258	ENSG00000168874
Uniprot IDs		B7Z3P6 P20815	Q96SQ7
PDB IDs		5VEU
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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