CYP3A4 and UGT2B7

  • Number of citations of the paper that reports this interaction (PubMedID 15611481)
  • 11
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology)
  • HPRD (in vitro, in vivo)

CYP3A4

UGT2B7

Description cytochrome P450 family 3 subfamily A member 4 UDP glucuronosyltransferase family 2 member B7
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Metabolic traits ( 21886157)
  • Neonatal cytokine/chemokine levels (maternal genetic effect) ( 30134952)
  • Pre-treatment viral load in HIV-1 infection ( 31219150)
  • Sex hormone levels ( 26014426)
  • Tacrolimus trough concentration in kidney transplant patients ( 29160300)
  • Ticagrelor levels in individuals with acute coronary syndromes treated with ticagrelor ( 25935875)
  • AR-C124910XX levels in individuals with acute coronary syndromes treated with ticagrelor ( 25935875)
  • Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644)
  • Estradiol levels ( 34255042)
  • Gamma glutamyl transferase levels ( 33339817)
  • Liver enzyme levels (alkaline phosphatase) ( 33972514)
  • Obesity-related traits ( 23251661)
  • Plasma clozapine-norclozapine ratio in treatment-resistant schizophrenia ( 30922102)
  • Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes 8 interacting genes: CYB5A CYP2C9 GK POR PRKACA PRKCA STUB1 UGT2B7 2 interacting genes: CYP3A4 GABRA3
Entrez ID 1576 7364
HPRD ID 00484 02508
Ensembl ID ENSG00000160868 ENSG00000171234
Uniprot IDs P08684 Q6GRK0 E9PBP8 P16662
PDB IDs 1TQN 1W0E 1W0F 1W0G 2J0D 2V0M 3NXU 3TJS 3UA1 4D6Z 4D75 4D78 4D7D 4I3Q 4I4G 4I4H 4K9T 4K9U 4K9V 4K9W 4K9X 4NY4 5A1P 5A1R 5G5J 5TE8 5VC0 5VCC 5VCD 5VCE 5VCG 6BCZ 6BD5 6BD6 6BD7 6BD8 6BDH 6BDI 6BDK 6BDM 6OO9 6OOA 6OOB 7KVH 7KVI 7KVJ 7KVK 7KVM 7KVN 7KVO 7KVP 7KVQ 7KVS 2O6L
Enriched GO Terms of Interacting Partners?
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