CYP2C8 and APOE

  • Number of citations of the paper that reports this interaction (PubMedID 21163940)
  • 36
  • Data Source:
  • BioGRID (two hybrid)

CYP2C8

APOE

Description cytochrome P450 family 2 subfamily C member 8 apolipoprotein E
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood metabolite levels ( 24816252)
  • Gout ( 22179738)
  • Immune response to smallpox vaccine (IL-6) ( 22542470)
  • Low density lipoprotein cholesterol levels ( 33339817)
  • Osteonecrosis of the jaw ( 18594024)
  • Plasma clozapine-norclozapine ratio in treatment-resistant schizophrenia ( 30922102)
  • Response to clopidogrel therapy ( 19706858)
  • Serum metabolite levels ( 33031748)
  • Total cholesterol levels ( 33339817)
  • Triglyceride levels in HIV infection ( 33109212)
  • Tuberculosis ( 24057671)
  • Urinary metabolite levels in chronic kidney disease ( 31959995)
  • Warfarin maintenance dose ( 23755828)
Interacting Genes 12 interacting genes: A2M APOE BLMH DNAJB1 ECSIT EXOC6 IFIT3 LONP1 MAST1 PSEN1 RIN3 RNF32 65 interacting genes: A2M ALB ANKH APOC2 APOC4 APP ARFGAP1 CD1D CD79A CDC37 CEACAM1 CNTF CSNK2A1 CST1 CTSB CYP2C18 CYP2C8 ECSIT ELAVL1 EPN2 FARSA FBXL12 FOXG1 FXYD7 GCDH HSP90AA1 HTRA1 IFIT3 IFIT5 IQSEC1 LCAT LDLR LINC02582 LONP1 LOXL4 LRP1 LRP2 LRP8 MAP2 MAPT MAST1 MID1IP1 NEFM NOS3 PCMT1 PDCD4 PLEKHA6 PLTP PRAM1 PRDX2 PRNP PSEN1 RHEB RNF32 RPL4 SCARB1 SNCA SORL1 ST13 TIMM29 TREM2 TYRO3 VLDLR ZBP1 ZNF558
Entrez ID 1558 348
HPRD ID 03083 00135
Ensembl ID ENSG00000138115 ENSG00000130203
Uniprot IDs B7Z1F5 P10632 A0A0S2Z3D5 P02649
PDB IDs 1PQ2 2NNH 2NNI 2NNJ 2VN0 1B68 1BZ4 1EA8 1GS9 1H7I 1LE2 1LE4 1LPE 1NFN 1NFO 1OEF 1OEG 1OR2 1OR3 2KC3 2KNY 2L7B 6IWB 6NCN 6NCO
Enriched GO Terms of Interacting Partners?
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