VKORC1L1 and PCYT1A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		VKORC1L1	PCYT1A
Description		vitamin K epoxide reductase complex subunit 1 like 1	phosphate cytidylyltransferase 1A, choline
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Nucleus Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Glycogen Granule
	Molecular Function	Protein Binding Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Quinone Binding	Choline-phosphate Cytidylyltransferase Activity Protein Binding Calmodulin Binding Phosphatidylcholine Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Peptidyl-glutamic Acid Carboxylation Cellular Response To Oxidative Stress Vitamin K Metabolic Process	Phosphatidylcholine Biosynthetic Process CDP-choline Pathway
Pathways		Metabolism of vitamin K	Synthesis of PC
Drugs		Menadione	Choline Choline salicylate
Diseases
GWAS		Calcium levels ( 24068962) Corneal structure ( 23291589) Estimated glomerular filtration rate ( 31152163) Intraocular pressure ( 30591961) Neutrophil count ( 32888494)	Mean platelet volume ( 32888494)
Interacting Genes		11 interacting genes: AQP6 CISD2 ERGIC3 GORAB GPX8 MRM1 MS4A3 MTIF3 PCYT1A PCYT1B TMEM80	16 interacting genes: ACTB AGTRAP CASP6 CASP8 FKBP7 GYS1 MAGEA3 MOB1A MOB3C PCYT1B RNF8 SCAMP1 SDCBP SNAPIN TNFRSF10D VKORC1L1
Entrez ID		154807	5130
HPRD ID		12312	00438
Ensembl ID		ENSG00000196715	ENSG00000161217
Uniprot IDs		A8K0F7 Q8N0U8	B4E322 P49585
PDB IDs
Enriched GO Terms of Interacting Partners?
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