PCYT1A and CASP6

Number of citations of the paper that reports this interaction (PubMedID 12052891)
23

Data Source:
HPRD (in vivo, in vitro)

		PCYT1A	CASP6
Description		phosphate cytidylyltransferase 1A, choline	caspase 6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Glycogen Granule	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Choline-phosphate Cytidylyltransferase Activity Protein Binding Calmodulin Binding Phosphatidylcholine Binding Identical Protein Binding Protein Homodimerization Activity	Cysteine-type Endopeptidase Activity Protein Binding Cysteine-type Peptidase Activity Identical Protein Binding Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cysteine-type Endopeptidase Activity Involved In Execution Phase Of Apoptosis
	Biological Process	Phosphatidylcholine Biosynthetic Process CDP-choline Pathway	Proteolysis Apoptotic Process Epithelial Cell Differentiation Cellular Response To Staurosporine Execution Phase Of Apoptosis
Pathways		Synthesis of PC	Apoptotic cleavage of cellular proteins Caspase-mediated cleavage of cytoskeletal proteins Breakdown of the nuclear lamina TP53 Regulates Transcription of Caspase Activators and Caspases
Drugs		Choline Choline salicylate
Diseases
GWAS		Mean platelet volume ( 32888494)	Risk-taking tendency (4-domain principal component model) ( 30643258)
Interacting Genes		16 interacting genes: ACTB AGTRAP CASP6 CASP8 FKBP7 GYS1 MAGEA3 MOB1A MOB3C PCYT1B RNF8 SCAMP1 SDCBP SNAPIN TNFRSF10D VKORC1L1	44 interacting genes: APP CASP10 CASP3 CASP8 CFLAR CHD3 COPS6 DSP EIF2S1 HSPD1 HTT IKBKG KRT18 LMNA LMNB1 LNX1 MAPK6 MAPT NEDD4 NTAQ1 NUAK1 PCYT1A PIN1 PKIA PPL PRKAB2 PRKCZ PSEN1 PSEN2 PSME3 RB1 RNF31 SATB1 SP1 SRF SRP72 STUB1 TAB1 TFAP2A TOP1 TRAF1 UBE4A UBE4B VIM
Entrez ID		5130	839
HPRD ID		00438	03321
Ensembl ID		ENSG00000161217	ENSG00000138794
Uniprot IDs		B4E322 P49585	P55212
PDB IDs			1MI9 2WDP 3K7E 3NKF 3NR2 3OD5 3P45 3P4U 3QNW 3S70 3S8E 3V6L 3V6M 4EJF 4FXO 4HVA 4IYR 4N5D 4N6G 4N7J 4N7M 4NBK 4NBL 4NBN 6DEU 6DEV
Enriched GO Terms of Interacting Partners?
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