AMOT and KRT24

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		AMOT	KRT24
Description		angiomotin	keratin 24
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Nucleoplasm Cytosol Actin Filament Plasma Membrane Bicellular Tight Junction External Side Of Plasma Membrane Lamellipodium Cell Junction Endocytic Vesicle Cytoplasmic Vesicle	Cytosol Intermediate Filament Extracellular Exosome
	Molecular Function	Protein Binding Signaling Receptor Activity Angiostatin Binding	Molecular_function Structural Molecule Activity Protein Binding
	Biological Process	Angiogenesis Vasculogenesis In Utero Embryonic Development Gastrulation With Mouth Forming Second Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Chemotaxis Negative Regulation Of Angiogenesis Actin Cytoskeleton Organization Regulation Of Cell Migration Negative Regulation Of GTPase Activity Cellular Protein Localization Hippo Signaling Positive Regulation Of Embryonic Development Cell Migration Involved In Gastrulation Blood Vessel Endothelial Cell Migration Regulation Of Small GTPase Mediated Signal Transduction	Biological_process
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31959851 30929738 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		57 interacting genes: ACTA1 AMOTL2 AP1M1 APP AQP1 AXIN2 C1orf216 CAPN3 DISC1 FHL2 HOXA1 HPCAL1 KIAA1328 KRT14 KRT15 KRT16 KRT19 KRT24 KRT27 KRT31 KRT34 KRT36 KRT75 LCE1D LMNB2 LMO4 LURAP1 LZTS1 MAGEA4 MAGI1 MAPK3 MED4 MEOX2 MIS18A MYBPC1 MYBPC2 MYOM3 NEDD4 NEDD4L NTAQ1 NUFIP2 PBLD PIK3C2A PIN1 PLG PRKAA2 PTEN PTPA RBM48 SEPTIN1 SLIRP SMC1A SNAPC5 SOCS6 THRA TTN UNC119	32 interacting genes: AARD ABI2 ABI3 AMOT BFSP2 C1orf109 C1orf216 CCDC146 CCHCR1 HGS KRT1 KRT20 KRT3 KRT4 KRT5 KRT6C KRT71 KRT72 KRT75 KRT79 KRT8 KRT80 ODAD3 PCM1 PRPH RCOR3 SGF29 SNAPIN TCHP TRIML2 TSGA10IP TXLNA
Entrez ID		154796	192666
HPRD ID		02327	09668
Ensembl ID		ENSG00000126016	ENSG00000167916
Uniprot IDs		Q4VCS5	Q2M2I5
PDB IDs		6JJX
Enriched GO Terms of Interacting Partners?
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