CXADR and AP3B1

		CXADR	AP3B1
Description		CXADR Ig-like cell adhesion molecule	adaptor related protein complex 3 subunit beta 1
Image			No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Extracellular Region Nucleoplasm Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Adherens Junction Bicellular Tight Junction Basolateral Plasma Membrane Apicolateral Plasma Membrane Cell Junction Filopodium Growth Cone Protein-containing Complex Neuron Projection Cell Body Membrane Raft	Mitochondrion Lysosomal Membrane Golgi Apparatus Membrane AP-3 Adaptor Complex Clathrin Adaptor Complex Clathrin-coated Vesicle Membrane Synapse Axon Cytoplasm
	Molecular Function	Virus Receptor Activity Integrin Binding Protein Binding Beta-catenin Binding PDZ Domain Binding Cell Adhesion Molecule Binding Connexin Binding Cell Adhesive Protein Binding Involved In AV Node Cell-bundle Of His Cell Communication	Protein Binding Protein Phosphatase Binding GTP-dependent Protein Binding
	Biological Process	Mitochondrion Organization Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Heart Development Germ Cell Migration Epithelial Structure Maintenance Neutrophil Chemotaxis Actin Cytoskeleton Reorganization Cell-cell Junction Organization Gamma-delta T Cell Activation Viral Entry Into Host Cell Cardiac Muscle Cell Development Transepithelial Transport AV Node Cell To Bundle Of His Cell Communication AV Node Cell-bundle Of His Cell Adhesion Involved In Cell Communication Regulation Of AV Node Cell Action Potential	Cell Morphogenesis Toll-like Receptor Signaling Pathway Hematopoietic Progenitor Cell Differentiation Respiratory System Process Cellular Protein Modification Process Protein Targeting To Lysosome Cellular Zinc Ion Homeostasis Intracellular Protein Transport Inflammatory Response Lysosome Organization Spermatogenesis Single Fertilization Blood Coagulation Anterograde Axonal Transport Synaptic Vesicle Budding From Endosome Vesicle-mediated Transport Granulocyte Differentiation Melanosome Organization Protein Localization To Cell Surface MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Homeostasis Of Number Of Cells Regulation Of Catalytic Activity Positive Regulation Of NK T Cell Differentiation Platelet Dense Granule Organization Lung Morphogenesis Establishment Of Protein Localization To Mitochondrial Membrane Involved In Mitochondrial Fission Skin Epidermis Development
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Cell surface interactions at the vascular wall	Golgi Associated Vesicle Biogenesis Signaling by BRAF and RAF1 fusions
Drugs
Diseases
GWAS		Neutrophil count ( 32888494) Serum alkaline phosphatase levels ( 33547301)	Adult body size ( 32376654) Body size at age 10 ( 32376654) Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697) FEV1 ( 30804560) Hip circumference adjusted for BMI ( 34021172) Insulin resistance/response ( 21901158) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lung function (FEV1) ( 30061609) Lung function (FVC) ( 30061609 30804560) Metabolite levels ( 23823483) Red cell distribution width ( 32888494) Serum alkaline phosphatase levels ( 33547301) Triglycerides ( 26780889) Type 2 diabetes ( 31049640)
Interacting Genes		13 interacting genes: ANKRD46 AP3B1 EWSR1 FAM3C JAML LNX1 LNX2 MAL NCOA1 NCOR1 OGT SRPK2 VKORC1	19 interacting genes: AP3D1 AP3S2 ARF1 ARF5 ARF6 ARR3 ATM ATR BUB1 BUB1B CLTC CSNK1A1 CXADR FCGR2B GKAP1 RNGTT SLC30A3 SSBP2 ZER1
Entrez ID		1525	8546
HPRD ID		11804	04551
Ensembl ID		ENSG00000154639	ENSG00000132842
Uniprot IDs		P78310	A0A0S2Z5J4 O00203
PDB IDs		1EAJ 1F5W 1JEW 1KAC 1P69 1P6A 1RSF 2J12 2J1K 2NPL 2W9L 2WBW 3J6L 3J6M 3J6N 3J6O
Enriched GO Terms of Interacting Partners?
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