CTSG and AGT

  • Number of citations of the paper that reports this interaction (PubMedID 10899625)
  • 59
  • Data Source:
  • HPRD (in vitro)

CTSG

AGT

Description cathepsin G angiotensinogen
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Congenital heart disease (maternal effect) ( 28468790)
  • Conotruncal heart defects (maternal effects) ( 28468790)
  • Blood protein levels ( 30072576)
  • Coronary artery disease ( 29212778 33020668)
  • Diastolic blood pressure ( 27841878 28739976 27618452)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Mean arterial pressure ( 27618448)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Pancreatic ductal adenocarcinoma ( 30541042)
  • Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
  • Systolic blood pressure ( 27841878 27618452 30578418)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes 31 interacting genes: AGT C3 CAMP CASP7 CXCL12 CXCR4 CYSRT1 ERBIN F2R F2RL1 F2RL2 F5 GP1BA HTR2A IGFBP3 KNG1 KRT31 LRP1 NOTCH2NLA PARP1 PICK1 PPBP SDC1 SELPLG SERPINA1 SERPINA3 SERPINB13 SERPINB4 SERPIND1 THBS1 VCAM1 24 interacting genes: ACE2 AGTR1 AGTR2 ATP6AP2 CMA1 CTSG DNPEP ECE1 ENPEP EWSR1 GRB2 GSDMB HSP90AA1 ITSN2 KNG1 LNPEP MAS1 MEP1A MME PRCP PREP PRG2 REN TP53
Entrez ID 1511 183
HPRD ID 00289 00106
Ensembl ID ENSG00000100448 ENSG00000135744
Uniprot IDs P08311 B0ZBE2 B2R5S1 P01019
PDB IDs 1AU8 1CGH 1KYN 1T32 6VTM 1N9U 1N9V 2JP8 2WXW 2X0B 3CK0 3WOO 3WOR 4AA1 4APH 4FYS 5E2Q 5M3X 5M3Y 5XJM 6I3F 6I3I 6JOD 6OS0 7C6A
Enriched GO Terms of Interacting Partners?
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