HORMAD2 and SYCP2

Number of citations of the paper that reports this interaction (PubMedID 30657449)
31

Data Source:
BioGRID (two hybrid, pull down)

		HORMAD2	SYCP2
Description		HORMA domain containing 2	synaptonemal complex protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Nucleus Nucleoplasm Chromosome Centrosome Cytosol	Synaptonemal Complex Lateral Element Nucleus
	Molecular Function	Protein Binding	DNA Binding
	Biological Process	Meiotic Sister Chromatid Cohesion Meiotic Cell Cycle	Mitotic G1 Phase Synaptonemal Complex Assembly Male Meiotic Nuclear Division Female Meiotic Nuclear Division Fertilization Negative Regulation Of Apoptotic Process Male Genitalia Morphogenesis Cell Division Meiotic Nuclear Division
Pathways			Meiotic synapsis
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Autoimmune thyroid disease ( 32581359) Behcet's disease ( 33393726) Cataracts ( 34127677) Creatine kinase levels ( 29403010) Crohn's disease ( 28067908) Delirium ( 29631748) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) IgA nephropathy ( 32912934 26028593 25305756) Inflammatory bowel disease ( 28067908) Inflammatory bowel disease (early onset) ( 19915574) Lymphocyte counts ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Mean corpuscular hemoglobin ( 32888494 27863252) Medication use (thyroid preparations) ( 31015401) Moyamoya disease ( 29273593) Nephropathy ( 21399633) Neutrophil percentage of white cells ( 32888494 27863252) Non-albumin protein levels ( 29403010) Optic cup area ( 31798171) Optic disc area ( 25631615) Tonsillectomy ( 27941131) Type 1 diabetes ( 30572963) Type 2 diabetes ( 30054458) Vertical cup-disc ratio ( 31798171) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Delirium ( 29631748)
Interacting Genes		2 interacting genes: NSD2 SYCP2	4 interacting genes: HORMAD2 SRPK2 SYCP3 USP13
Entrez ID		150280	10388
HPRD ID		13668	06822
Ensembl ID		ENSG00000176635	ENSG00000196074
Uniprot IDs		Q8N7B1	Q9BX26
PDB IDs
Enriched GO Terms of Interacting Partners?
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