SYCP2 and HORMAD2

Number of citations of the paper that reports this interaction (PubMedID 30657449)
31

Data Source:
BioGRID (two hybrid, pull down)

		SYCP2	HORMAD2
Description		synaptonemal complex protein 2	HORMA domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Lateral Element Nucleus	Synaptonemal Complex Nucleus Nucleoplasm Chromosome Centrosome Cytosol
	Molecular Function	DNA Binding	Protein Binding
	Biological Process	Mitotic G1 Phase Synaptonemal Complex Assembly Male Meiotic Nuclear Division Female Meiotic Nuclear Division Fertilization Negative Regulation Of Apoptotic Process Male Genitalia Morphogenesis Cell Division Meiotic Nuclear Division	Meiotic Sister Chromatid Cohesion Meiotic Cell Cycle
Pathways		Meiotic synapsis
Drugs
Diseases
GWAS		Delirium ( 29631748)	Albumin-globulin ratio ( 29403010) Autoimmune thyroid disease ( 32581359) Behcet's disease ( 33393726) Cataracts ( 34127677) Creatine kinase levels ( 29403010) Crohn's disease ( 28067908) Delirium ( 29631748) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) IgA nephropathy ( 32912934 26028593 25305756) Inflammatory bowel disease ( 28067908) Inflammatory bowel disease (early onset) ( 19915574) Lymphocyte counts ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Mean corpuscular hemoglobin ( 32888494 27863252) Medication use (thyroid preparations) ( 31015401) Moyamoya disease ( 29273593) Nephropathy ( 21399633) Neutrophil percentage of white cells ( 32888494 27863252) Non-albumin protein levels ( 29403010) Optic cup area ( 31798171) Optic disc area ( 25631615) Tonsillectomy ( 27941131) Type 1 diabetes ( 30572963) Type 2 diabetes ( 30054458) Vertical cup-disc ratio ( 31798171) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		4 interacting genes: HORMAD2 SRPK2 SYCP3 USP13	2 interacting genes: NSD2 SYCP2
Entrez ID		10388	150280
HPRD ID		06822	13668
Ensembl ID		ENSG00000196074	ENSG00000176635
Uniprot IDs		Q9BX26	Q8N7B1
PDB IDs
Enriched GO Terms of Interacting Partners?
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