LCA5L and SUV39H2

Number of citations of the paper that reports this interaction (PubMedID 23455924)
46

Data Source:
BioGRID (two hybrid)

		LCA5L	SUV39H2
Description		lebercilin LCA5 like	SUV39H2 histone lysine methyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Axoneme	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm
	Molecular Function	Protein Binding	Transcription Cis-regulatory Region Binding Protein Binding Zinc Ion Binding Histone-lysine N-methyltransferase Activity Histone Methyltransferase Activity (H3-K9 Specific) S-adenosyl-L-methionine Binding
	Biological Process	Intraciliary Transport	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Assembly Or Disassembly Chromatin Remodeling Cell Cycle Cell Differentiation Histone Lysine Methylation Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Cellular Response To Hypoxia
Pathways			PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Low density lipoprotein cholesterol levels ( 32154731) Pulse pressure ( 30224653) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		22 interacting genes: B3GALT5-AS1 CCDC136 CCDC197 DSCR8 EXOSC5 FCHSD2 IKBIP KRT75 KRT76 KRT80 KRT81 NMI PBXIP1 PRPH RIPPLY3 SUV39H2 SYCE1L TFIP11 TPM3 TSGA10IP ZDHHC17 ZGPAT	41 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GOLGA6L9 GSTCD ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 ODAD3 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 WIZ ZNF212 ZNF557 ZNF57
Entrez ID		150082	79723
HPRD ID		10742	07580
Ensembl ID		ENSG00000157578	ENSG00000152455
Uniprot IDs		O95447	Q9H5I1
PDB IDs			2R3A 6P0R
Enriched GO Terms of Interacting Partners?
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