GATA5 and HPCAL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GATA5	HPCAL1
Description		GATA binding protein 5	hippocalcin like 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Membrane
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific Double-stranded DNA Binding	Calcium Ion Binding Protein Binding
	Biological Process	Aortic Valve Morphogenesis Endocardial Cushion Fusion Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Notch Signaling Pathway Involved In Heart Induction Cell Fate Commitment Positive Regulation Of Transcription By RNA Polymerase II Cardiac Muscle Tissue Development Intestinal Epithelial Cell Differentiation Positive Regulation Of Cardiac Endothelial To Mesenchymal Transition Cellular Response To BMP Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Benign prostatic hyperplasia and lower urinary tract symptoms ( 30410027) Central serous retinopathy ( 31872073) Chronic central serous retinopathy ( 30073298) Diastolic blood pressure ( 33230300) Hematocrit ( 32888494) Hemoglobin ( 32888494) Prostate cancer ( 23535732) Systolic blood pressure ( 33230300)	Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Kidney function decline traits ( 25493955) Lung function (FEV1/FVC) ( 30061609) Platelet distribution width ( 32888494)
Interacting Genes		10 interacting genes: ARID5A CYSRT1 EP300 HNF1A HPCA HPCAL1 KLF2 MAGED1 PLA2G10 PPARG	38 interacting genes: AMOT ATXN1 C19orf44 C1QTNF2 CA3 COLGALT2 CREM DTX2 EFEMP2 EPHB3 FZD7 GATA5 HMG20A IKBKG KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP17-1 KRTAP4-2 KRTAP5-9 LITAF MDFI MICOS10-NBL1 MYDGF NBL1 NBPF19 NOTCH2NLA PLAAT2 SERPINI2 SLC34A1 TPSG1 VWC2 ZNF655
Entrez ID		140628	3241
HPRD ID		17029	02564
Ensembl ID		ENSG00000130700	ENSG00000115756
Uniprot IDs		Q9BWX5	O75544 P37235 Q6FGY1
PDB IDs			5T7C
Enriched GO Terms of Interacting Partners?
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