GATA5 and HPCA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GATA5	HPCA
Description		GATA binding protein 5	hippocalcin
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Cytoplasm Cytosol Extrinsic Component Of Membrane Axon Dendrite Membrane Neuronal Cell Body Membrane Dendrite Cytoplasm Perikaryon Dendritic Spine Head Glutamatergic Synapse
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific Double-stranded DNA Binding	Actin Binding Calcium Ion Binding Protein Binding Kinase Binding Identical Protein Binding
	Biological Process	Aortic Valve Morphogenesis Endocardial Cushion Fusion Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Notch Signaling Pathway Involved In Heart Induction Cell Fate Commitment Positive Regulation Of Transcription By RNA Polymerase II Cardiac Muscle Tissue Development Intestinal Epithelial Cell Differentiation Positive Regulation Of Cardiac Endothelial To Mesenchymal Transition Cellular Response To BMP Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development	Brain Development Calcium-mediated Signaling Negative Regulation Of Guanylate Cyclase Activity Activation Of Phospholipase D Activity Positive Regulation Of Adenylate Cyclase Activity Inner Ear Development Retina Development In Camera-type Eye Cellular Response To Electrical Stimulus Cellular Response To Calcium Ion Positive Regulation Of Protein Targeting To Membrane Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Regulation Of Voltage-gated Calcium Channel Activity Response To Ketamine Response To L-glutamate Cellular Response To Monosodium Glutamate Response To Aroclor 1254
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Benign prostatic hyperplasia and lower urinary tract symptoms ( 30410027) Central serous retinopathy ( 31872073) Chronic central serous retinopathy ( 30073298) Diastolic blood pressure ( 33230300) Hematocrit ( 32888494) Hemoglobin ( 32888494) Prostate cancer ( 23535732) Systolic blood pressure ( 33230300)	Daytime nap ( 33568662)
Interacting Genes		10 interacting genes: ARID5A CYSRT1 EP300 HNF1A HPCA HPCAL1 KLF2 MAGED1 PLA2G10 PPARG	28 interacting genes: APC BMP8B C1QTNF2 CKMT1A CKMT1B CREM CSF3R DPYD DTX2 E2F2 GATA5 IL36RN MLLT10 MYDGF NAIP NDC80 NMT1 NUDC PRR35 RAE1 RUNX3 SLC16A3 TEPSIN TMEM54 TNFRSF8 TUBA4A UQCRB VWC2
Entrez ID		140628	3208
HPRD ID		17029	00811
Ensembl ID		ENSG00000130700	ENSG00000121905
Uniprot IDs		Q9BWX5	P84074
PDB IDs			5G4P 5G58 5M6C
Enriched GO Terms of Interacting Partners?
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