NEK7 and ZBTB41

		NEK7	ZBTB41
Description		NIMA related kinase 7	zinc finger and BTB domain containing 41
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleoplasm Cytoplasm Microtubule Organizing Center Microtubule	Nucleus
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding Protein Serine Kinase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Metal Ion Binding
	Biological Process	Protein Phosphorylation Regulation Of Mitotic Cell Cycle Positive Regulation Of Telomere Maintenance Via Telomerase Spindle Assembly Positive Regulation Of Telomerase Activity Positive Regulation Of Telomere Capping	Regulation Of Transcription By RNA Polymerase II
Pathways		Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Pore Complex (NPC) Disassembly EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Height ( 28552196) High altitude adaptation ( 28373541) Pulse pressure ( 33230300)	Age-related macular degeneration ( 23536807) Blood protein levels ( 28240269) Lupus nephritis in systemic lupus erythematosus ( 24925725)
Interacting Genes		8 interacting genes: C1orf53 EML4 LYN NEK9 PPP1R13B TERF1 TNNI1 ZBTB41	2 interacting genes: DENND1B NEK7
Entrez ID		140609	360023
HPRD ID		06027	17017
Ensembl ID		ENSG00000151414	ENSG00000177888
Uniprot IDs		B2R8K8 Q8TDX7	Q5SVQ8
PDB IDs		2WQM 2WQN 5DE2 6NPY 6S73 6S75 6S76
Enriched GO Terms of Interacting Partners?
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