CNTN1 and NOTCH1

  • Number of citations of the paper that reports this interaction (PubMedID 14567914)
  • 130
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vitro, in vivo)

CNTN1

NOTCH1

Description contactin 1 notch receptor 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Antidepressant treatment resistance (> 2 drugs prescribed) ( 30700811)
  • Blood protein levels ( 30072576)
  • Body mass index ( 26426971)
  • Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872)
  • Dementia and core Alzheimer's disease neuropathologic changes ( 25188341)
  • Metabolite levels (X-11787) ( 23934736)
  • Motion sickness ( 25628336)
  • Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
  • Pneumoconiosis in silica exposure ( 24986923)
  • Protein quantitative trait loci ( 18464913)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
  • Crohn's disease ( 28067908)
  • Eosinophil counts ( 32888494)
  • Inflammatory bowel disease ( 28067908)
  • Length of menstrual cycle ( 26732621)
  • Mean corpuscular hemoglobin ( 32888494)
  • Red cell distribution width ( 28957414)
  • Serum alkaline phosphatase levels ( 33547301)
  • Triglyceride levels ( 32203549)
  • Ulcerative colitis ( 28067908)
Interacting Genes 14 interacting genes: CNTN2 FYN GPR37 L1CAM MAPK6 NOTCH1 NOTCH2 PPP1CA PRNP PTPRB SCN3A SCNN1B TNC TNR 87 interacting genes: ADAM17 AKT1 APBA1 ARL6IP5 B3GALT4 BLOC1S1 CACNA1A CAMK4 CASR CBL CCN3 CEP57L1 CNTN1 COL4A6 CTNNB1 DAZAP2 DLL1 DLL4 DTX1 DTX2 EGFL7 EP300 EXT1 FAM185A FBP1 FBXW7 FURIN GFI1B GOLGA2 GOPC GSK3B HMGN5 HOXA1 ILK ITCH JAG1 JAG2 KAT2A KAT2B KIAA1191 LCK LEF1 LFNG LINC00260 LINC02907 LNX2 MAGEA1 MAGED1 MAML1 MAML2 MAML3 MAP3K1 MBD1 MDM2 MEF2C MFNG NFKB1 NUMB NUMBL PIK3CG POFUT1 POU2AF1 PRKCD PSEN1 PSEN2 RBP3 RBPJ REL RELA RHOA RUNX3 SHANK3 SMAD3 SNAI1 SNW1 STC1 TLE3 TOR1A USP10 USP12 USP2 USP7 WDR12 WWP1 XIAP XRCC6 YY1
Entrez ID 1272 4851
HPRD ID 07189 01827
Ensembl ID ENSG00000018236 ENSG00000148400
Uniprot IDs A0A024R104 Q12860 P46531
PDB IDs 2EE2 3S97 1PB5 1TOZ 1YYH 2F8X 2F8Y 2HE0 2VJ3 3ETO 3I08 3L95 3NBN 3V79 4CUD 4CUE 4CUF 4D0E 4D0F 5FM9 5FMA 5KZO 5L0R 5UB5 6IDF 6PY8
Enriched GO Terms of Interacting Partners?
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