TARS3 and TARS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TARS3	TARS2
Description		threonyl-tRNA synthetase 3	threonyl-tRNA synthetase 2, mitochondrial
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleus Cytoplasm	Cellular_component Mitochondrial Matrix
	Molecular Function	Molecular_function Threonine-tRNA Ligase Activity Protein Binding ATP Binding	Aminoacyl-tRNA Editing Activity Threonine-tRNA Ligase Activity Protein Binding ATP Binding Protein Homodimerization Activity
	Biological Process	Threonyl-tRNA Aminoacylation Biological_process	Threonyl-tRNA Aminoacylation Mitochondrial Threonyl-tRNA Aminoacylation Aminoacyl-tRNA Metabolism Involved In Translational Fidelity
Pathways			Mitochondrial tRNA aminoacylation
Drugs			Threonine
Diseases
GWAS			Alanine aminotransferase levels ( 33547301) Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823 27494321) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) LDL cholesterol levels ( 32203549) Liver enzyme levels (alanine transaminase) ( 33972514) Morning person ( 30696823) Morning vs. evening chronotype ( 27494321) Plateletcrit ( 32888494) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		11 interacting genes: ARPC3 ARRDC4 ATF4 DNM1P46 ECSIT LGALS14 LRRC28 SELENOS TARS1 TARS2 TM2D3	15 interacting genes: ANP32E ARL6IP1 ASB6 CIART FKBP7 GABPB2 H3C14 HOMEZ PLIN3 SLC17A9 SYPL1 TARS3 TNFAIP8L2 TNFRSF10D ZNF687
Entrez ID		123283	80222
HPRD ID		15469	18148
Ensembl ID		ENSG00000185418	ENSG00000143374
Uniprot IDs		A2RTX5	Q9BW92 U3KQG0
PDB IDs
Enriched GO Terms of Interacting Partners?
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