SLC41A2 and GJB5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLC41A2	GJB5
Description		solute carrier family 41 member 2	gap junction protein beta 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Connexin Complex Integral Component Of Membrane
	Molecular Function	Protein Binding Magnesium Ion Transmembrane Transporter Activity	Gap Junction Channel Activity Protein Binding
	Biological Process	Magnesium Ion Transmembrane Transport	Cell-cell Signaling Epidermis Development Transmembrane Transport Trophoblast Giant Cell Differentiation Labyrinthine Layer Morphogenesis Epididymis Development
Pathways		Metal ion SLC transporters	Gap junction assembly
Drugs
Diseases
GWAS		Beta blocker survival benefit in heart failure with reduced ejection fraction (time to all cause mortality x beta blocker interaction) ( 33012170) glucocorticoid receptor gene expression in B-cell precursor acute lymphoblastic leukaemia ( 33002292)	BMI x environmental factors (excluding physical activity) interaction ( 33654129) BMI x environmental factors (including physical activity) interaction ( 33654129) Narcolepsy ( 23459209) Sleep duration (short sleep) ( 30846698) Triglyceride levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		32 interacting genes: AQP6 CD79A CKAP4 CLN5 CREB3 EBP ERGIC3 ERVFRD-1 FATE1 FNDC9 FUT3 GJA5 GJB5 GPR151 GPR42 GPX8 IGFBP5 IL27RA KASH5 KIR3DL3 LDLRAD1 LEUTX LIME1 LMNA LY6G6C LYVE1 MFF PDCD1LG2 PVR SHISAL1 SSMEM1 TMEM237	45 interacting genes: APOL2 APOL3 AQP1 C1GALT1 C4orf3 COMT CTXN3 CYB5B DNALI1 ERG28 FAM3C GSK3B IGFBP5 JAGN1 LMNA LPAR3 LRP10 MED1 MIP MS4A13 MYL2 NAPB PCGF2 PGAP2 PLPP4 PLPP6 PNLIPRP1 RPRM RTP2 SEC22A SEC22B SERP1 SLC30A2 SLC38A7 SLC41A1 SLC41A2 SMIM1 TM4SF4 TMEM128 TMEM60 TMEM86A TMEM97 TRIM2 TSPO2 VSTM1
Entrez ID		84102	2709
HPRD ID		15389	06840
Ensembl ID		ENSG00000136052	ENSG00000189280
Uniprot IDs		Q96JW4	A0A654IE64 O95377
PDB IDs
Enriched GO Terms of Interacting Partners?
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