CLK3 and HOXC4

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

CLK3

HOXC4

Description CDC like kinase 3 homeobox C4
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bladder cancer ( 25281661)
  • Caffeine metabolism (plasma 1,3,7-trimethylxanthine (caffeine) level) ( 27702941)
  • Caffeine metabolism (plasma 1,3-dimethylxanthine (theophylline) level) ( 27702941)
  • Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941)
  • Celiac disease ( 22057235)
  • Coffee consumption (cups per day) ( 31837886)
  • Craniofacial microsomia ( 26853712)
  • Body shape index ( 34021172)
  • Coronary artery disease ( 32469254)
  • Diastolic blood pressure ( 27841878)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Medication use (calcium channel blockers) ( 31015401)
  • Pulse pressure ( 27841878 30578418)
  • Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Response to fenofibrate (LDL cholesterol levels) ( 27002377)
  • Systolic blood pressure ( 27841878 27618447 30578418)
  • Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Triglyceride levels ( 32203549)
  • Waist circumference ( 28552196)
  • Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
  • Waist circumference adjusted for BMI in active individuals ( 28448500)
  • Waist circumference adjusted for body mass index ( 28552196 34021172 28448500)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172 26426971)
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 25673412)
Interacting Genes 41 interacting genes: APP CHERP CLASRP CLK2 DDIT4L HOXB6 HOXB7 HOXC4 INCA1 KRTAP10-3 LNX1 NEDD4 NKAPL NXF1 OAS2 PRMT5 RBMX RBMY1A1 RBMY1F RNF8 RNPS1 RSRP1 SAG SDCBP SH2B2 SLAMF7 SNIP1 SNRNP35 SRPK2 SRSF10 SRSF3 SRSF8 SUV39H1 TINF2 TRA2B USP13 YWHAG ZNF263 ZNF473 ZNF777 ZNF835 17 interacting genes: APP CLK3 CSNK2A1 ELMOD2 EXOSC5 HTT NCK2 NSD3 PRKDC PRMT5 PRMT6 RCHY1 RNF32 RPRD1B SOX10 SUV39H1 XRCC6
Entrez ID 1198 3221
HPRD ID 04290 00860
Ensembl ID ENSG00000179335 ENSG00000198353
Uniprot IDs B3KRI8 P49761 A0A024RB51 P09017 Q86TF7
PDB IDs 2EU9 2EXE 2WU6 2WU7 3RAW 6FT7 6FYP 6FYR 6KHF 6RCT 6YTW 6YTY 6YU1 6Z2V 6Z51 6Z52 6Z53 6Z54 6Z55
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?