CLK3 and CLASRP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CLK3	CLASRP
Description		CDC like kinase 3	CLK4 associating serine/arginine rich protein
Image			No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Nucleus Nucleoplasm Membrane Nuclear Speck Intermediate Filament Cytoskeleton	Nucleoplasm
	Molecular Function	RNA Binding Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Binding ATP Binding Identical Protein Binding Protein Serine Kinase Activity	Protein Binding
	Biological Process	Protein Phosphorylation Peptidyl-tyrosine Phosphorylation Regulation Of RNA Splicing Protein Autophosphorylation	MRNA Processing RNA Splicing
Pathways
Drugs		K-00546 ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate Fostamatinib
Diseases
GWAS		Bladder cancer ( 25281661) Caffeine metabolism (plasma 1,3,7-trimethylxanthine (caffeine) level) ( 27702941) Caffeine metabolism (plasma 1,3-dimethylxanthine (theophylline) level) ( 27702941) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941) Celiac disease ( 22057235) Coffee consumption (cups per day) ( 31837886) Craniofacial microsomia ( 26853712)	Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971)
Interacting Genes		41 interacting genes: APP CHERP CLASRP CLK2 DDIT4L HOXB6 HOXB7 HOXC4 INCA1 KRTAP10-3 LNX1 NEDD4 NKAPL NXF1 OAS2 PRMT5 RBMX RBMY1A1 RBMY1F RNF8 RNPS1 RSRP1 SAG SDCBP SH2B2 SLAMF7 SNIP1 SNRNP35 SRPK2 SRSF10 SRSF3 SRSF8 SUV39H1 TINF2 TRA2B USP13 YWHAG ZNF263 ZNF473 ZNF777 ZNF835	15 interacting genes: APP ATXN1 CDK6 CFAP20 CLK1 CLK2 CLK3 CLK4 DAB1 DAZAP2 DYRK1A RHOXF2 SMAD3 SRPK2 VDR
Entrez ID		1198	11129
HPRD ID		04290	11552
Ensembl ID		ENSG00000179335	ENSG00000104859
Uniprot IDs		B3KRI8 P49761	A0A0A0MQS2 Q8N2M8
PDB IDs		2EU9 2EXE 2WU6 2WU7 3RAW 6FT7 6FYP 6FYR 6KHF 6RCT 6YTW 6YTY 6YU1 6Z2V 6Z51 6Z52 6Z53 6Z54 6Z55
Enriched GO Terms of Interacting Partners?
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