SH2D1B and LY9

Number of citations of the paper that reports this interaction (PubMedID 11689425)
35

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		SH2D1B	LY9
Description		SH2 domain containing 1B	lymphocyte antigen 9
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Plasma Membrane External Side Of Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity	Molecular_function
	Biological Process	Adaptive Immune Response Leukocyte Activation Involved In Immune Response Positive Regulation Of Natural Killer Cell Mediated Immunity Innate Immune Response Positive Regulation Of Innate Immune Response	Cell Adhesion Positive Regulation Of Interleukin-17 Production T Cell Activation Innate Immune Response T-helper 17 Cell Lineage Commitment
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Sum of carotid plaque area ( 32469969) Sum of stenosis ( 32469969) Takayasu arteritis ( 25604533)	Blood protein levels ( 29875488 28240269) Lymphocyte counts ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) White blood cell count ( 32888494)
Interacting Genes		26 interacting genes: AGR2 APP AR BLK CD244 CD84 EGFR ERBB2 ERBB3 ERBB4 FCRLA GAB1 KIT LY9 MAGEB4 MAPK8IP2 MEOX2 MET NFKBID NUTM1 PRDX1 PTK2 SLAMF1 STAT4 TNK2 TRIM54	5 interacting genes: AP2M1 C1orf68 CD48 SH2D1A SH2D1B
Entrez ID		117157	4063
HPRD ID		12248	02817
Ensembl ID		ENSG00000198574	ENSG00000122224
Uniprot IDs		O14796	A0A0C4DFU4 Q05CA2 Q0VAI0 Q5VYH9 Q9HBG7
PDB IDs		5KAZ
Enriched GO Terms of Interacting Partners?
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