EVI5L and TBC1D21

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		EVI5L	TBC1D21
Description		ecotropic viral integration site 5 like	TBC1 domain family member 21
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Acrosomal Vesicle Cytoskeleton Extracellular Exosome
	Molecular Function	GTPase Activator Activity Protein Binding Small GTPase Binding	Actin Binding GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Intracellular Protein Transport Positive Regulation Of GTPase Activity Activation Of GTPase Activity Negative Regulation Of Cilium Assembly	Intracellular Protein Transport Spermatogenesis Cell Differentiation Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) HIV-1 viral setpoint ( 20205591) Menarche (age at onset) ( 25231870)	Coffee consumption (cups per day) ( 31837886) Estimated glomerular filtration rate ( 31152163) Exfoliation glaucoma or exfoliation syndrome ( 24938310) Feeling fed-up ( 29500382) Glucose homeostasis traits ( 25524916) LDL cholesterol levels in HIV infection ( 33109212)
Interacting Genes		16 interacting genes: A2M ANKRD36 AP1M1 CCDC185 GAS8 KRT79 LNX1 NUDT18 ODAD3 PRPF18 PSEN2 RAB10 RBM7 SRPK2 TBC1D21 ZNF648	29 interacting genes: APP CCDC158 CFAP53 EVI5L GAS2 GFAP GTF2E1 KIF26A KRT15 KRT35 KRT37 KRT38 KRT40 LCN2 MEOX2 NR1D2 NUTM1 PDCD2 PMF1 PMF1-BGLAP RAB3IP REL RIBC1 SAMD4A SEPTIN2 SNX7 STMN3 TCF12 TIMM10
Entrez ID		115704	161514
HPRD ID		10044	15473
Ensembl ID		ENSG00000142459	ENSG00000167139
Uniprot IDs		A0A384MR55 Q96CN4	Q8IYX1
PDB IDs
Enriched GO Terms of Interacting Partners?
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