TBC1D21 and GAS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TBC1D21	GAS2
Description		TBC1 domain family member 21	growth arrest specific 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cytoskeleton Extracellular Exosome	Cytosol Actin Filament Membrane
	Molecular Function	Actin Binding GTPase Activator Activity Protein Binding Small GTPase Binding	Microtubule Binding Cytoskeletal Anchor Activity Actin Filament Binding
	Biological Process	Intracellular Protein Transport Spermatogenesis Cell Differentiation Activation Of GTPase Activity Regulation Of Cilium Assembly	Initiation Of Primordial Ovarian Follicle Growth Antral Ovarian Follicle Growth Apoptotic Process Cell Cycle Regulation Of Cell Shape Regulation Of Notch Signaling Pathway Ovulation Actin Crosslink Formation Basement Membrane Organization
Pathways			Caspase-mediated cleavage of cytoskeletal proteins
Drugs
Diseases
GWAS		Coffee consumption (cups per day) ( 31837886) Estimated glomerular filtration rate ( 31152163) Exfoliation glaucoma or exfoliation syndrome ( 24938310) Feeling fed-up ( 29500382) Glucose homeostasis traits ( 25524916) LDL cholesterol levels in HIV infection ( 33109212)	Dialysis-related mortality ( 21546767) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Metabolite levels ( 23823483)
Interacting Genes		29 interacting genes: APP CCDC158 CFAP53 EVI5L GAS2 GFAP GTF2E1 KIF26A KRT15 KRT35 KRT37 KRT38 KRT40 LCN2 MEOX2 NR1D2 NUTM1 PDCD2 PMF1 PMF1-BGLAP RAB3IP REL RIBC1 SAMD4A SEPTIN2 SNX7 STMN3 TCF12 TIMM10	4 interacting genes: ACTA1 APP CAPN2 TBC1D21
Entrez ID		161514	2620
HPRD ID		15473	04158
Ensembl ID		ENSG00000167139	ENSG00000148935
Uniprot IDs		Q8IYX1	O43903
PDB IDs
Enriched GO Terms of Interacting Partners?
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