TENT5B and PLK4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TENT5B	PLK4
Description		terminal nucleotidyltransferase 5B	polo like kinase 4
Image		No pdb structure
GO Annotations	Cellular Component		Spindle Pole XY Body Nucleus Nucleolus Cytoplasm Centrosome Centriole Cytosol Cleavage Furrow Deuterosome
	Molecular Function	Protein Binding RNA Adenylyltransferase Activity	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Identical Protein Binding Protein Serine Kinase Activity
	Biological Process	MRNA Stabilization	Mitotic Cell Cycle Protein Phosphorylation Centriole Replication Regulation Of Cytokinesis Positive Regulation Of Centriole Replication Cilium Assembly Trophoblast Giant Cell Differentiation De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs			Fostamatinib
Diseases
GWAS
Interacting Genes		61 interacting genes: ACY1 AKAP8L AKAP9 ATXN1 BHLHE40 C10orf55 C3orf36 CERCAM CYSRT1 DAZAP2 ENKD1 FAM166B FAM168B FOS FOSB FOXI1 HIVEP1 HMGXB4 HNRNPF KLHL38 KRT34 KRTAP19-6 KRTAP6-1 KRTAP6-2 MGAT5B MKRN3 NAF1 NICN1 NR1D2 OTX2 PLK4 POU2AF1 POU6F2 PROP1 PSMB8 PSMF1 RBPMS2 RFX6 RHOXF2 RIMBP3C RUSC1 SLC15A2 SLC27A4 SMAP2 SOHLH1 SOX5 SPAG8 TBX6 TENT5A TLE5 TNS2 TRIP13 UBAP2 UBQLN2 USP54 YPEL3 ZBTB2 ZC3H10 ZNF503 ZNF620 ZNF688	22 interacting genes: ARR3 BTRC C1orf109 CHD3 CYLD DNAJB13 ELOA GAS8 MTUS2 OSBPL3 PRDM16 SFN SMAD4 SPAG5 TAX1BP3 TEC TENT5B TENT5C TFIP11 TGFBR1 TRIM54 ZBTB39
Entrez ID		115572	10733
HPRD ID		16882	10387
Ensembl ID		ENSG00000158246	ENSG00000142731
Uniprot IDs		Q96A09	O00444
PDB IDs			2N19 3COK 4JXF 4N7V 4N7Z 4N9J 4YUR 4YYP 5LHY 5LHZ 6N45 6N46 6W38 6W3I 6W3J
Enriched GO Terms of Interacting Partners?
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