FBXO17 and OAS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FBXO17	OAS2
Description		F-box protein 17	2'-5'-oligoadenylate synthetase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol SCF Ubiquitin Ligase Complex	Nucleoplasm Cytosol Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Activity	2'-5'-oligoadenylate Synthetase Activity Double-stranded RNA Binding Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Glycoprotein Catabolic Process Protein Ubiquitination Ubiquitin-dependent ERAD Pathway SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process	Nucleobase-containing Compound Metabolic Process RNA Catabolic Process Response To Virus Positive Regulation Of Interferon-beta Production Positive Regulation Of Tumor Necrosis Factor Production Defense Response To Bacterium Negative Regulation Of Viral Genome Replication Defense Response To Virus Type I Interferon Signaling Pathway Regulation Of Ribonuclease Activity Interleukin-27-mediated Signaling Pathway Regulation Of Lactation
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Interferon gamma signaling OAS antiviral response Interferon alpha/beta signaling
Drugs
Diseases
GWAS		SAPHO syndrome ( 33816493)	Adult asthma ( 27611488) Body mass index ( 26426971) Coffee consumption ( 29367735) Low HDL-cholesterol levels ( 31006500) Response to fenofibrate (adiponectin levels) ( 23149075) Retinitis pigmentosa ( 33514863) Thalamus volume ( 31530798) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		22 interacting genes: ADAMTSL4 ADRB2 CBY2 CDCA8 DZIP3 EIF4H JRK KPRP KRT75 KRTAP13-2 LASP1 OAS2 PTPN21 RAB11FIP2 RUNX1 SAXO1 SAXO2 SKP1 USP54 ZNF213 ZNF829 ZSCAN9	3 interacting genes: APP CLK3 FBXO17
Entrez ID		115290	4939
HPRD ID		16436	04518
Ensembl ID		ENSG00000269190	ENSG00000111335
Uniprot IDs		Q96EF6	P29728 Q7Z6D0
PDB IDs
Enriched GO Terms of Interacting Partners?
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