MRFAP1L1 and ABI3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		MRFAP1L1	ABI3
Description		Morf4 family associated protein 1 like 1	ABI family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Intracellular Anatomical Structure Cytoplasm Postsynaptic Density Membrane Lamellipodium SCAR Complex Dendritic Spine Dendritic Shaft
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding SH3 Domain Binding Identical Protein Binding Actin Filament Binding
	Biological Process		Defense Response To Tumor Cell Negative Regulation Of Lamellipodium Assembly Peptidyl-tyrosine Phosphorylation Regulation Of Cell Migration Regulation Of Dendritic Spine Morphogenesis Regulation Of Postsynaptic Density Assembly Negative Regulation Of Ruffle Assembly Negative Regulation Of Protein Localization To Plasma Membrane Regulation Of Actin Cytoskeleton Reorganization Positive Regulation Of Cellular Senescence
Pathways
Drugs
Diseases
GWAS			Alzheimer's disease (late onset) ( 28714976) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Asthma ( 31619474) Family history of Alzheimer's disease ( 30617256) Prostate cancer ( 23535732) Refractive error ( 32231278)
Interacting Genes		47 interacting genes: ABI1 ABI2 ABI3 BYSL C1orf216 C3orf62 CAGE1 CAVIN3 CDK2AP1 CDK2AP2 CENPK CEP44 CNOT7 CSPP1 EIF2B2 GAS8 GTF2IRD1 HGS HTT IHO1 JAKMIP1 LMO2 LNX1 LNX2 MEOX2 MORF4L1 MORF4L2 MRFAP1 NTAQ1 PIH1D2 PIK3R2 PSMA1 RADIL RDM1 SDCBP SFR1 SMARCE1 SMU1 SYCE1 TCF4 TEX11 TMEM126B TSNAX TXN2 UBTD1 ZDHHC17 ZNF417	77 interacting genes: ABI2 ABI3BP ACTN3 AGTR1 ARHGAP9 ARMC7 BAIAP2L2 BFSP2 BLOC1S5 CENPQ CEP170P1 CEP44 CYFIP2 DESI1 DTNB DTNBP1 EIF3H EIF3M EMILIN1 ENAH EVL FAM124B FARSA FBF1 GNG13 GOLM1 GRB2 HOMER1 HOMER2 HOMER3 IFT20 IHO1 KANK2 KIAA0408 KIFC3 KLC3 KLC4 KRT13 KRT14 KRT15 KRT24 KRT28 KRT31 KRT35 KRT36 KRT38 MAGEA12 MED29 MIS18A MRFAP1 MRFAP1L1 NCK2 NDEL1 NHSL2 NUP58 OIP5 PAK1 PAK2 PSMA1 RUFY3 RUNX1T1 SH3BP1 SMARCD1 SNAP23 SOS1 STX1A STX2 SUFU TMEM147 TRAF4 TXN2 VARS2 VASP WAS WASF1 WASF2 WASHC1
Entrez ID		114932	51225
HPRD ID		15162	05900
Ensembl ID		ENSG00000178988	ENSG00000108798
Uniprot IDs		A0A075DDR2 Q96HT8	Q9P2A4
PDB IDs
Enriched GO Terms of Interacting Partners?
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