MAL2 and NDRG4

Number of citations of the paper that reports this interaction (PubMedID 26871637)
172

Data Source:
BioGRID (two hybrid, two hybrid)

		MAL2	NDRG4
Description		mal, T cell differentiation protein 2	NDRG family member 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endomembrane System Integral Component Of Membrane Apical Plasma Membrane Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome	Cytoplasm Mitochondrion Endoplasmic Reticulum Membrane Cytosol Basolateral Plasma Membrane Cell Projection Membrane
	Molecular Function	Protein Binding Structural Constituent Of Myelin Sheath	Molecular_function Protein Binding
	Biological Process	Myelination Transcytosis	Heart Looping Signal Transduction Brain Development Visual Learning Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Negative Regulation Of Smooth Muscle Cell Migration Cell Differentiation Embryonic Heart Tube Development Vesicle Docking Negative Regulation Of Smooth Muscle Cell Proliferation Cardiac Muscle Cell Proliferation Cell Migration Involved In Heart Development Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Endocytic Recycling
Pathways
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Blood pressure (smoking interaction) ( 25189868) Gallstone disease ( 30504769) Hippocampal atrophy ( 19668339) Osteoprotegerin levels ( 25080503)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 20062063) Liver enzyme levels (alanine transaminase) ( 33972514) Oily fish consumption ( 32066663) Pork consumption ( 32066663) QT interval ( 22726844 19305408 19305409) Schizophrenia ( 29483656)
Interacting Genes		50 interacting genes: ABCG8 AQP6 ARFIP2 ARL13B ATP6V0E1 CD160 CD68 CHAF1B COQ8A CREB3 CREB3L1 ECPAS FAM3A GAD1 GAD2 GJB1 GPR152 HSFX1 HSFX2 MRM1 MTERF3 MUC1 NDRG4 NFAM1 PBX3 PIMREG PITPNC1 POLL PPP1CA PTPN9 RAB37 REEP4 RETREG3 S100B SCN3B SGK1 SH3GL1 SH3GLB1 SHMT2 SLC35C2 SUCLA2 TBRG4 THAP4 TMEM14B TPD52 TPD52L1 TPD52L2 TTPA TUBB VARS2	41 interacting genes: ADCY9 AGTRAP ALDH6A1 APLNR ARFIP2 ARL6IP1 ATP5PF CACFD1 CDR1 CIDEB CMTM3 CMTM5 COQ3 CPLX2 DERL3 DGAT2L6 DHX38 ERGIC3 LEUTX LIME1 LRRC59 MAL2 MTIF3 NOL3 PLP2 PRAF2 RABAC1 REEP6 RTN3 SCAMP1 SDR16C5 SFT2D2 SGK1 SIN3A SMPD2 SYNGR1 SYNGR3 SYP THAP4 TMEM208 YIF1A
Entrez ID		114569	65009
HPRD ID		14351	14817
Ensembl ID		ENSG00000147676	ENSG00000103034
Uniprot IDs		A0A024R9E4 Q969L2	A0A024R6V8 A0A0S2Z5L7 A0A0S2Z5R7 B7Z9X4 Q9ULP0
PDB IDs
Enriched GO Terms of Interacting Partners?
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