MAL2 and VARS2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		MAL2	VARS2
Description		mal, T cell differentiation protein 2	valyl-tRNA synthetase 2, mitochondrial
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endomembrane System Integral Component Of Membrane Apical Plasma Membrane Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome	Mitochondrion Cytosol
	Molecular Function	Protein Binding Structural Constituent Of Myelin Sheath	Aminoacyl-tRNA Editing Activity Valine-tRNA Ligase Activity Protein Binding ATP Binding
	Biological Process	Myelination Transcytosis	Valyl-tRNA Aminoacylation Aminoacyl-tRNA Metabolism Involved In Translational Fidelity
Pathways			Mitochondrial tRNA aminoacylation
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Blood pressure (smoking interaction) ( 25189868) Gallstone disease ( 30504769) Hippocampal atrophy ( 19668339) Osteoprotegerin levels ( 25080503)	Autism spectrum disorder or schizophrenia ( 28540026) Chronic obstructive pulmonary disease ( 33909500) Conotruncal heart defects (maternal effects) ( 28468790) Gestational age at birth (maternal effect) ( 28877031) HIV-1 control ( 20041166) Malaria ( 31844061) Microalbuminuria in type 1 diabetes ( 31537649) Pubertal anthropometrics ( 23449627) Refractive error ( 32231278) Squamous cell lung carcinoma ( 28604730) Ulcerative colitis ( 20848476) Urate levels ( 31578528)
Interacting Genes		50 interacting genes: ABCG8 AQP6 ARFIP2 ARL13B ATP6V0E1 CD160 CD68 CHAF1B COQ8A CREB3 CREB3L1 ECPAS FAM3A GAD1 GAD2 GJB1 GPR152 HSFX1 HSFX2 MRM1 MTERF3 MUC1 NDRG4 NFAM1 PBX3 PIMREG PITPNC1 POLL PPP1CA PTPN9 RAB37 REEP4 RETREG3 S100B SCN3B SGK1 SH3GL1 SH3GLB1 SHMT2 SLC35C2 SUCLA2 TBRG4 THAP4 TMEM14B TPD52 TPD52L1 TPD52L2 TTPA TUBB VARS2	8 interacting genes: ABI1 ABI2 ABI3 CMTM5 MAL2 NCK2 PIK3CA SORBS3
Entrez ID		114569	57176
HPRD ID		14351	11670
Ensembl ID		ENSG00000147676	ENSG00000137411
Uniprot IDs		A0A024R9E4 Q969L2	A0A1U9X9B3 B4DG77 B4E0K6 Q5ST30
PDB IDs
Enriched GO Terms of Interacting Partners?
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