CHRNB4 and LARP7

CHRNB4

LARP7

Description cholinergic receptor nicotinic beta 4 subunit La ribonucleoprotein 7, transcriptional regulator
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Attention function in attention deficit hyperactive disorder ( 26174813)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Benign childhood epilepsy with centro-temporal spikes ( 32580138)
  • BMI (smoking interaction) ( 28443625)
  • BMI in smokers ( 28443625)
  • Body mass index (joint analysis main effects and smoking interaction) ( 28443625)
  • Chronic obstructive pulmonary disease ( 30804561)
  • Chronic obstructive pulmonary disease x ever smoker interaction (1df) ( 33106845)
  • Coronary artery disease ( 32469254 33020668)
  • Diffusing capacity of carbon monoxide ( 30694715)
  • Exhaled carbon monoxide levels ( 25072098)
  • Gut microbiota relative abundance (Parabacteroides) ( 33208821)
  • Lung adenocarcinoma ( 28604730)
  • Lung cancer ( 31577861 28604730 18385738 18780872)
  • Lung cancer in ever smokers ( 28604730)
  • Nicotine dependence ( 18385739 26440539)
  • Post bronchodilator FEV1 ( 26634245)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
  • Refractive error ( 32231278)
  • Schizophrenia ( 25056061 29483656)
  • Small cell lung carcinoma ( 28604730)
  • Smoking status (heavy vs light) ( 28520984)
  • Squamous cell lung carcinoma ( 28604730)
  • Sudden cardiac arrest ( 21658281)
  • Body mass index ( 26426971)
  • Brain morphology (MOSTest) ( 32665545)
  • Cortical surface area (MOSTest) ( 32665545)
  • Dental caries (decayed and filled deciduous teeth) ( 31533690)
  • Meat-related diet ( 32066663)
  • Subcortical volume (MOSTest) ( 32665545)
Interacting Genes 8 interacting genes: CHRNA2 CHRNA3 CHRNA4 CHRNA5 LARP7 MEOX2 SLC2A1 UBQLN1 89 interacting genes: APP BARD1 BRCA1 CHRNB4 GABRG2 GAR1 JMJD6 LRRK2 MCUB MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I OSTC PAPSS1 PPA2 PRPF40A PUF60 RN7SK RRH SMS ZGRF1
Entrez ID 1143 51574
HPRD ID 00337 17095
Ensembl ID ENSG00000117971 ENSG00000174720
Uniprot IDs P30926 Q4G0J3
PDB IDs 2ASG 6PV7 6PV8 4WKR 5KNW 6D12
Enriched GO Terms of Interacting Partners?
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