CHRNB4 and CHRNA2

  • Number of citations of the paper that reports this interaction (PubMedID 8906617)
  • 15
  • Data Source:
  • HPRD (in vivo, in vitro)

CHRNB4

CHRNA2

Description cholinergic receptor nicotinic beta 4 subunit cholinergic receptor nicotinic alpha 2 subunit
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Attention function in attention deficit hyperactive disorder ( 26174813)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Benign childhood epilepsy with centro-temporal spikes ( 32580138)
  • BMI (smoking interaction) ( 28443625)
  • BMI in smokers ( 28443625)
  • Body mass index (joint analysis main effects and smoking interaction) ( 28443625)
  • Chronic obstructive pulmonary disease ( 30804561)
  • Chronic obstructive pulmonary disease x ever smoker interaction (1df) ( 33106845)
  • Coronary artery disease ( 32469254 33020668)
  • Diffusing capacity of carbon monoxide ( 30694715)
  • Exhaled carbon monoxide levels ( 25072098)
  • Gut microbiota relative abundance (Parabacteroides) ( 33208821)
  • Lung adenocarcinoma ( 28604730)
  • Lung cancer ( 31577861 28604730 18385738 18780872)
  • Lung cancer in ever smokers ( 28604730)
  • Nicotine dependence ( 18385739 26440539)
  • Post bronchodilator FEV1 ( 26634245)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
  • Refractive error ( 32231278)
  • Schizophrenia ( 25056061 29483656)
  • Small cell lung carcinoma ( 28604730)
  • Smoking status (heavy vs light) ( 28520984)
  • Squamous cell lung carcinoma ( 28604730)
  • Sudden cardiac arrest ( 21658281)
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Cannabis use disorder ( 33096046 31209380)
  • Lung cancer ( 28604730)
  • Response to zileuton treatment in asthma (FEV1 change interaction) ( 26031901)
  • Schizophrenia ( 29483656)
  • Smoking status (current vs mixed) ( 33082346)
  • Smoking status (current vs never) ( 33082346)
Interacting Genes 8 interacting genes: CHRNA2 CHRNA3 CHRNA4 CHRNA5 LARP7 MEOX2 SLC2A1 UBQLN1 2 interacting genes: CHRNB2 CHRNB4
Entrez ID 1143 1135
HPRD ID 00337 00332
Ensembl ID ENSG00000117971 ENSG00000120903
Uniprot IDs P30926 Q15822
PDB IDs 2ASG 6PV7 6PV8 5FJV
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?