MED8 and HSPB3

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MED8	HSPB3
Description		mediator complex subunit 8	heat shock protein family B (small) member 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mediator Complex Core Mediator Complex	Nucleus Cytoplasm Nuclear Speck
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Coregulator Activity Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Protein Ubiquitination	Response To Unfolded Protein
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Feeling worry ( 29500382) Schizophrenia ( 28991256) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Systolic blood pressure (dietary potassium intake interaction) ( 29212900)
Interacting Genes		32 interacting genes: APP ARRB2 CCNC CDK8 CTDP1 ELOC HSPB3 KRT40 MED1 MED11 MED12 MED17 MED19 MED20 MED22 MED25 MED26 MED27 MED28 MED30 MED31 MED6 MED7 MED9 PEX14 PHYHIP PNMA1 PRKAR1B SNTA1 THOC7 UBALD1 USP49	19 interacting genes: ANP32A BBOX1 HSPB2 HSPB8 LRIF1 LSM14B MED31 MED8 MRPL38 NSMF OLFML3 PRPF4B RAMP3 RBM48 RTL8A SETDB1 TCAP UNC119 ZZEF1
Entrez ID		112950	8988
HPRD ID		06991	06861
Ensembl ID		ENSG00000159479	ENSG00000169271
Uniprot IDs		Q96G25	Q12988 Q6ICS9
PDB IDs			6F2R
Enriched GO Terms of Interacting Partners?
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