ZWINT and CLU

  • Number of citations of the paper that reports this interaction (PubMedID 17974975)
  • 9
  • Data Source:
  • BioGRID (two hybrid)

ZWINT

CLU

Description ZW10 interacting kinetochore protein clusterin
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cardiac hypertrophy ( 21348951)
  • Cognitive function in longevity ( 33607172)
  • Erosive tooth wear (severe vs non-severe) ( 29898447)
  • Erosive tooth wear (severe vs none or mild) ( 29898447)
  • Liver fibrosis (total hepatic collagen content) ( 32953199)
  • Alzheimer's disease ( 19734902 19734903 21627779 31473137)
  • Alzheimer's disease (late onset) ( 21460841 30617256 24162737 28714976)
  • Alzheimer's disease in APOE e4+ carriers ( 25778476)
  • Alzheimer's disease in APOE e4- carriers ( 25778476)
  • Alzheimer's disease or family history of Alzheimer's disease ( 33589840 30617256)
  • Alzheimer's disease or fasting insulin levels (pleiotropy) ( 30805717)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Family history of Alzheimer's disease ( 30617256)
  • Lung adenocarcinoma ( 28604730)
  • Lung cancer in ever smokers ( 28604730)
  • Panic disorder ( 19165232)
  • Refractive error ( 32231278)
  • Schizophrenia ( 25056061 29483656)
  • Smoking behaviour (cigarettes smoked per day) ( 31089300)
  • Smoking initiation ( 33082346)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes 17 interacting genes: APP BCAS2 BFSP1 CCHCR1 CLU DSN1 FAM90A1 KRT75 LIG4 MAFB MIS12 MSGN1 NDC80 NUP54 PHAX TSG101 ZW10 59 interacting genes: ADGRF4 APP BAG6 C7 C8B C9 CBR3 CBY1 CD209 CLUAP1 CYP2E1 DISC1 DLG4 DUSP13 ELN EPPIN FOS GEMIN7 GRB2 HSPD1 IL24 KATNA1 KEAP1 KLF11 KNSTRN KRT12 LEP LEPR LIG4 LRP1 LRP2 LRP8 LYZ MAPK9 MDM2 MMP25 MSRB1 NAT2 PAXIP1 PLXNA4 POLR1C PON1 PRNP RBBP8 RPL23 SHANK3 SRPK2 SYVN1 TGFBR1 TGFBR2 TNIK TREM2 TSC22D4 TTR UBC VHL VLDLR XRCC6 ZWINT
Entrez ID 11130 1191
HPRD ID 18366 01706
Ensembl ID ENSG00000122952 ENSG00000120885
Uniprot IDs O95229 P10909
PDB IDs
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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