CLU and PON1

  • Number of citations of the paper that reports this interaction (PubMedID 8292612)
  • 25
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo, in vitro)

CLU

PON1

Description clusterin paraoxonase 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease ( 19734902 19734903 21627779 31473137)
  • Alzheimer's disease (late onset) ( 21460841 30617256 24162737 28714976)
  • Alzheimer's disease in APOE e4+ carriers ( 25778476)
  • Alzheimer's disease in APOE e4- carriers ( 25778476)
  • Alzheimer's disease or family history of Alzheimer's disease ( 33589840 30617256)
  • Alzheimer's disease or fasting insulin levels (pleiotropy) ( 30805717)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Family history of Alzheimer's disease ( 30617256)
  • Lung adenocarcinoma ( 28604730)
  • Lung cancer in ever smokers ( 28604730)
  • Panic disorder ( 19165232)
  • Refractive error ( 32231278)
  • Schizophrenia ( 25056061 29483656)
  • Smoking behaviour (cigarettes smoked per day) ( 31089300)
  • Smoking initiation ( 33082346)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes 59 interacting genes: ADGRF4 APP BAG6 C7 C8B C9 CBR3 CBY1 CD209 CLUAP1 CYP2E1 DISC1 DLG4 DUSP13 ELN EPPIN FOS GEMIN7 GRB2 HSPD1 IL24 KATNA1 KEAP1 KLF11 KNSTRN KRT12 LEP LEPR LIG4 LRP1 LRP2 LRP8 LYZ MAPK9 MDM2 MMP25 MSRB1 NAT2 PAXIP1 PLXNA4 POLR1C PON1 PRNP RBBP8 RPL23 SHANK3 SRPK2 SYVN1 TGFBR1 TGFBR2 TNIK TREM2 TSC22D4 TTR UBC VHL VLDLR XRCC6 ZWINT 3 interacting genes: ALB APOA1 CLU
Entrez ID 1191 5444
HPRD ID 01706 01351
Ensembl ID ENSG00000120885 ENSG00000005421
Uniprot IDs P10909 P27169
PDB IDs 1V04 1XHR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?