HIBADH and NDUFB11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HIBADH	NDUFB11
Description		3-hydroxyisobutyrate dehydrogenase	NADH:ubiquinone oxidoreductase subunit B11
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I
	Molecular Function	Protein Binding 3-hydroxyisobutyrate Dehydrogenase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor NADP Binding NAD Binding	Protein Binding
	Biological Process	Valine Catabolic Process Branched-chain Amino Acid Catabolic Process	Mitochondrial Respiratory Chain Complex I Assembly
Pathways		Branched-chain amino acid catabolism	Respiratory electron transport Complex I biogenesis
Drugs		NADH
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258) Asthma ( 31959851) Diastolic blood pressure ( 27841878) General risk tolerance (MTAG) ( 30643258) Kidney stones ( 31729369) Lead levels in blood ( 25820613) Pulse pressure ( 27841878) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Systolic blood pressure ( 27841878)
Interacting Genes		39 interacting genes: ADAM33 AGTRAP AIG1 AMELY AQP3 ASGR1 BRCA1 C2CD2L CDS2 CLEC2A CMTM7 CNIH2 COMT CTSA EFNA5 ERMP1 GOSR2 MAL NDUFB11 PAEP PLN PRAF2 PTCH1 RTP2 SCARB2 SEC22B SFT2D2 SNORC TFRC TM6SF2 TMEM14B TMEM222 TMEM60 TMEM86B TRIM63 UBIAD1 VAMP2 VAMP5 ZFPL1	11 interacting genes: BAG6 CLDN7 EBP FATE1 GJB1 GPR101 GPR152 GPR42 HIBADH PPBP TIMMDC1
Entrez ID		11112	54539
HPRD ID		12238	02323
Ensembl ID		ENSG00000106049	ENSG00000147123
Uniprot IDs		A0A024RA75 P31937	Q9NX14
PDB IDs		2GF2 2I9P	5XTC 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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