HIBADH and SNORC

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HIBADH	SNORC
Description		3-hydroxyisobutyrate dehydrogenase	secondary ossification center associated regulator of chondrocyte maturation
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Extracellular Region Cytoplasm Integral Component Of Membrane Collagen-containing Extracellular Matrix Cell Periphery
	Molecular Function	Protein Binding 3-hydroxyisobutyrate Dehydrogenase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor NADP Binding NAD Binding	Protein Binding
	Biological Process	Valine Catabolic Process Branched-chain Amino Acid Catabolic Process	Cartilage Development
Pathways		Branched-chain amino acid catabolism
Drugs		NADH
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258) Asthma ( 31959851) Diastolic blood pressure ( 27841878) General risk tolerance (MTAG) ( 30643258) Kidney stones ( 31729369) Lead levels in blood ( 25820613) Pulse pressure ( 27841878) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Systolic blood pressure ( 27841878)
Interacting Genes		39 interacting genes: ADAM33 AGTRAP AIG1 AMELY AQP3 ASGR1 BRCA1 C2CD2L CDS2 CLEC2A CMTM7 CNIH2 COMT CTSA EFNA5 ERMP1 GOSR2 MAL NDUFB11 PAEP PLN PRAF2 PTCH1 RTP2 SCARB2 SEC22B SFT2D2 SNORC TFRC TM6SF2 TMEM14B TMEM222 TMEM60 TMEM86B TRIM63 UBIAD1 VAMP2 VAMP5 ZFPL1	24 interacting genes: AQP6 CD53 CISD2 EBP ELOVL4 ERGIC3 FAM209A GPX8 HIBADH HSD17B13 KIR2DL3 LHFPL2 LMNA LRRC59 MGST3 SLC10A6 SLC14A1 SLC26A6 SLC7A8 STX1A TMEM31 TMEM45B TMEM86B ZDHHC15
Entrez ID		11112	389084
HPRD ID		12238	15620
Ensembl ID		ENSG00000106049	ENSG00000182600
Uniprot IDs		A0A024RA75 P31937	A0A6M4NK13 Q6UX34
PDB IDs		2GF2 2I9P
Enriched GO Terms of Interacting Partners?
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