ATE1 and PLEKHA1

		ATE1	PLEKHA1
Description		arginyltransferase 1	pleckstrin homology domain containing A1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Ruffle Membrane Extracellular Exosome
	Molecular Function	Arginyltransferase Activity Protein Binding	Protein Binding Lipid Binding PDZ Domain Binding Phosphatidylinositol-3,4-bisphosphate Binding
	Biological Process	Proteasomal Protein Catabolic Process Protein Arginylation	Luteinization Spermatogenesis Androgen Metabolic Process Estrogen Metabolic Process Post-embryonic Development Phosphatidylinositol 3-kinase Signaling Ruffle Organization Leydig Cell Differentiation Multicellular Organism Growth Establishment Of Protein Localization Platelet-derived Growth Factor Receptor Signaling Pathway Skeletal System Morphogenesis B Cell Receptor Signaling Pathway Negative Regulation Of Protein Kinase B Signaling Roof Of Mouth Development Face Morphogenesis Cellular Response To Hydrogen Peroxide
Pathways			Synthesis of PIPs at the plasma membrane
Drugs			Citric acid
Diseases
GWAS		Chronotype ( 30696823)	Age-related macular degeneration ( 23577725 23536807) Age-related macular degeneration (extreme sampling) ( 23577725) Autoimmune thyroid disease ( 32581359) Birth weight ( 31043758 27680694) Central corneal thickness ( 32528159) Femoral neck bone mineral density ( 29499414) Height ( 31562340 20189936) Hip circumference adjusted for BMI ( 34021172) Medication use (thyroid preparations) ( 31015401) Offspring birth weight ( 31043758) Refractive error ( 32231278) Type 1 diabetes in high risk HLA genotype individuals (time to event) ( 29310926) Type 2 diabetes ( 28566273 24509480 30054458 30297969 32499647 30718926 28869590)
Interacting Genes		14 interacting genes: ABRAXAS2 ACADSB ALCAM CTBP2 FAM53B INTS8 NEDD8 NSMCE4A NTAN1 NUP188 PLEKHA1 RBM10 SUV39H1 TIMM17B	9 interacting genes: ATE1 CLDN14 CRKL FBXO7 MPDZ PLEKHA2 PTPN13 SH3BP4 SNTG1
Entrez ID		11101	59338
HPRD ID		06979	09686
Ensembl ID		ENSG00000107669	ENSG00000107679
Uniprot IDs		B3KWA3 B4DK25 B4E107 F5GXE4 F8WAC9 O95260	B3KQL5 Q5RGS4 Q9HB21
PDB IDs			1EAZ
Enriched GO Terms of Interacting Partners?
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