WWP1 and ARRDC1

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		WWP1	ARRDC1
Description		WW domain containing E3 ubiquitin protein ligase 1	arrestin domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Cytoplasm Cytosol Plasma Membrane Extracellular Exosome	Cytoplasm Plasma Membrane Cytoplasmic Vesicle Extracellular Exosome Extracellular Vesicle
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Activity	Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Ubiquitin Ligase-substrate Adaptor Activity Arrestin Family Protein Binding
	Biological Process	Protein Polyubiquitination Signal Transduction Central Nervous System Development Protein Ubiquitination Ion Transmembrane Transport Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Negative Regulation Of Transcription, DNA-templated Viral Entry Into Host Cell	Ubiquitin-dependent Protein Catabolic Process Extracellular Transport Protein Transport Protein Ubiquitination Negative Regulation Of Notch Signaling Pathway Extracellular Vesicle Biogenesis
Pathways		Downregulation of ERBB4 signaling Stimuli-sensing channels Regulation of RUNX2 expression and activity Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31152163)	Asthma ( 32296059) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433)
Interacting Genes		58 interacting genes: ARRDC1 ARRDC2 ARRDC3 ASH2L ATN1 CLCN5 CPSF6 DAG1 DAZAP2 DIDO1 DVL2 EWSR1 FAM189A2 FBXL18 HSPB1 IKBKG IL2RG IL6R KLF2 KLF5 LAPTM5 LATS1 LNX1 LZTR1 MACROH2A2 MIR19A MIR19B1 NFE2 NOTCH1 PCBD1 PHF20L1 PRKAA2 PRRG4 PYGM RASA1 RNF11 RTN4 RUNX1 SCNN1A SFTPC SHANK3 SMAD3 SMAD5 STAT6 TFAP2A TGIF1 TP53BP2 TRAF4 UBC UBE2D1 UBE2D2 UBE2D3 UBE2L3 WASL WBP1 WBP2 YWHAQ ZNF638	11 interacting genes: APP DAPK1 EPN2 KLHL12 MTDH MTURN PDCD6IP TSG101 UBASH3A WWP1 WWP2
Entrez ID		11059	92714
HPRD ID		03811	12491
Ensembl ID		ENSG00000123124	ENSG00000197070
Uniprot IDs		Q9H0M0	Q8N5I2
PDB IDs		1ND7 2OP7 5HPS 5HPT 6J1X 6J1Y
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?