KIF2C and CENPH

Number of citations of the paper that reports this interaction (PubMedID 11092768)
29

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		KIF2C	CENPH
Description		kinesin family member 2C	centromere protein H
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Nucleus Centrosome Spindle Cytosol Kinesin Complex Microtubule Cytoplasmic Microtubule Microtubule Cytoskeleton Membrane Microtubule Plus-end	Kinetochore Nucleus Nucleoplasm Chromosome Nucleolus Cytosol
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP Hydrolysis Activity Centromeric DNA Binding Microtubule Plus-end Binding	Protein Binding Kinetochore Binding
	Biological Process	Microtubule-based Movement Microtubule Depolymerization Mitotic Metaphase Plate Congression Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Cell Division Metaphase Plate Congression Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Chromosome Segregation	Mitotic Spindle Organization Chromosome Segregation Kinetochore Assembly Kinetochore Organization
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins COPI-dependent Golgi-to-ER retrograde traffic Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation Kinesins	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs		Phosphoaminophosphonic Acid-Adenylate Ester
Diseases
GWAS
Interacting Genes		14 interacting genes: APP AURKA CENPH CSNK2B DRD4 H3-4 KDM4A NDEL1 PLK1 PMPCA SUMO2 TOMM70 VHL ZNF566	18 interacting genes: ABI2 C1orf216 C8orf58 CCDC146 DCTN2 ERH H2AP KIF2C LMNB1 MESD MTAP NDC80 NUF2 NUP54 RASSF4 SPAG5 ZNF493 ZSCAN12
Entrez ID		11004	64946
HPRD ID		05172	12029
Ensembl ID		ENSG00000142945	ENSG00000153044
Uniprot IDs		A0A140VKF1 B7Z6Q6 B7Z7M6 Q99661	A0A0S2Z5T0 Q9H3R5
PDB IDs		2HEH 4UBF 4Y05 5MIO
Enriched GO Terms of Interacting Partners?
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