FASTK and TOP3B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FASTK	TOP3B
Description		Fas activated serine/threonine kinase	DNA topoisomerase III beta
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Matrix Ribonucleoprotein Granule	Condensed Chromosome Nucleus
	Molecular Function	RNA Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Fas-activated Serine/threonine Kinase Activity	DNA Binding RNA Binding DNA Topoisomerase Activity DNA Topoisomerase Type I (single Strand Cut, ATP-independent) Activity Protein Binding
	Biological Process	Mitochondrial RNA Processing Protein Phosphorylation Regulation Of RNA Splicing Regulation Of Mitochondrial MRNA Stability Apoptotic Signaling Pathway	DNA Topological Change Chromosome Segregation
Pathways
Drugs
Diseases
GWAS		Eyebrow thickness ( 26926045)	Attention function in attention deficit hyperactive disorder ( 26174813) Bipolar disorder ( 31043756) Diastolic blood pressure ( 29208002) Response to selective serotonin reuptake inhibitors in depression ( 27622933)
Interacting Genes		9 interacting genes: CALCOCO2 CHERP ESRRG MDFI PRPF31 RBPMS TIA1 TOP3B WIPF1	24 interacting genes: ADAMTSL4 AXIN2 BHLHB9 C1QBP CENPF CHD8 CHIC2 CIAO1 FASTK FBLN5 GRN KANK2 KRTAP4-12 MID2 PNMA2 RECQL5 SNRPB SPRED2 SSX2IP TRIM41 UPF2 ZFPM1 ZNF250 ZNF408
Entrez ID		10922	8940
HPRD ID		07368	04662
Ensembl ID		ENSG00000164896	ENSG00000100038
Uniprot IDs		A0A090N8I0 A0A090N8Z7 Q14296	A0A024R1C2 A8K4N2 O95985
PDB IDs			5GVC 5GVE
Enriched GO Terms of Interacting Partners?
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