PGRMC1 and CAMLG

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PGRMC1	CAMLG
Description		progesterone receptor membrane component 1	calcium modulating ligand
Image
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Endomembrane System Membrane Smooth Endoplasmic Reticulum Membrane Specific Granule Membrane Neuron Projection Neuronal Cell Body Cell Body Synapse	Cytoplasm Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane GET Complex
	Molecular Function	Amyloid-beta Binding Steroid Binding Protein Binding Heme Binding Protein Homodimerization Activity Metal Ion Binding	Protein Binding Ubiquitin Protein Ligase Binding Cell Adhesion Molecule Binding
	Biological Process	Heme Biosynthetic Process	B Cell Homeostasis Defense Response Signal Transduction Vesicle-mediated Transport Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Stabilization Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways		Neutrophil degranulation	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs		Dextromethorphan Nortriptyline Sertraline	Cyclosporine
Diseases
GWAS		Hodgkin's lymphoma ( 34216518)	Height ( 18391951)
Interacting Genes		21 interacting genes: BIK CAMLG CCDC134 CENPU CIAO1 CREB3L1 DEFB124 EVI2B GET3 GLP1R GOLM1 KASH5 KCNE5 MTNR1A MX1 PAM16 PGRMC2 SCAP SGTB TMEM213 ZNF71	22 interacting genes: ADIPOQ AGR2 EGFR ETNK1 F11R GET1 GET3 HSP90B1 KCNA2 KCNE4 LAT LCN2 OCIAD1 PBXIP1 PGRMC1 PKHD1 PPIB STT3B TMEM31 TNFRSF13B TXNDC12 VWC2
Entrez ID		10857	819
HPRD ID		02338	03073
Ensembl ID		ENSG00000101856	ENSG00000164615
Uniprot IDs		O00264 Q6IB11	P49069
PDB IDs		4X8Y	6SO5
Enriched GO Terms of Interacting Partners?
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